Literature DB >> 17338761

Improving patency of coronary conduits "valveless" veins and/or arterial grafts.

Thomas Z Lajos1, Francis Robicsek, Mano Thubrikar, Harold Urschel.   

Abstract

BACKGROUND: Veins used for coronary artery bypass operation have a well-documented limited long-term patency. Internal thoracic artery (ITA) grafts have shown exceptional "durability." Assumptions were made that other arterial conduits have similar characteristics. AIM OF THE STUDY: The purpose of this article is to compare different conduits long-term patency including saphenous veins to other available arterial conduits: inferior epigastric artery (IE), right gastroepiploic artery (RGEA), and radial artery (RA).
METHODS: Recent studies have shown that radial artery bypasses have lower patency rate than saphenous veins. Flow patterns, physiological flow characteristics are reviewed including native vessel disease and area of myocardium supplied. In the case of venous bypasses, the primary culprit of failure seemed to be the quality of the vein itself and the reverse venous valves in the conduit resulting in: (a) trapping-hypertension, (b) thrombosis, (c) turbulence, (d) intimal damage, (e) mismatching in size.
RESULTS: Clinical follow-up of our patients up to 8 to 11 years (average 8.9 years) have proved the superior characteristics of the so-called "good veins." In a retrospective study of 436 patients sequential, valveless veins patency was 88.6% versus 72% of reversed valvular segments (p < 0.01). Patients' survival seemed to be significantly improved if these veins were combined with ITA grafts. Patients' survival with one valveless limb HS + ITA was 78% versus HS + SV 52% (p < or = 0.0017) and HS + ITA versus HS + ITA + SV (p < 0.0057).
CONCLUSION: Selective decision-making of the surgeon at the time of the operation is required to choose the best conduit to be able to perform the best operation with the best long-term result.

Entities:  

Mesh:

Year:  2007        PMID: 17338761     DOI: 10.1111/j.1540-8191.2007.00380.x

Source DB:  PubMed          Journal:  J Card Surg        ISSN: 0886-0440            Impact factor:   1.620


  3 in total

Review 1.  Mechanisms of vein graft adaptation to the arterial circulation: insights into the neointimal algorithm and management strategies.

Authors:  Akihito Muto; Lynn Model; Kenneth Ziegler; Sammy D D Eghbalieh; Alan Dardik
Journal:  Circ J       Date:  2010-07-01       Impact factor: 2.993

2.  Intraoperative Analysis of Flow Dynamics in Arteriovenous Composite Y Grafts.

Authors:  Heraldo Guedis Lobo; José Glauco Lobo; Matheus Duarte Pimentel; Bruno Gadelha Bezerra Silva; Camylla Santos de Souza; Marília Leitão Montenegro; Maria Cláudia de Azevedo Leitão; Francisco Vagnaldo Fechine Jamacuru
Journal:  Braz J Cardiovasc Surg       Date:  2016 Sep-Oct

3.  Reply: Valveless saphenous vein grafts for coronary artery bypass grafting: First, do no harm.

Authors:  Oz M Shapira
Journal:  JTCVS Open       Date:  2021-09-06
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.