Literature DB >> 17337538

Bacterial degradation of N,N-diethyl-m-toluamide (DEET): cloning and heterologous expression of DEET hydrolase.

Giomar Rivera-Cancel1, Daniela Bocioaga, Anthony G Hay.   

Abstract

Pseudomonas putida DTB grew aerobically with N,N-diethyl-m-toluamide (DEET) as a sole carbon source, initially breaking it down into 3-methylbenzoate and diethylamine. The former was further metabolized via 3-methylcatechol and meta ring cleavage. A gene from DTB, dthA, was heterologously expressed and shown to encode the ability to hydrolyze DEET into 3-methylbenzoate and diethylamine.

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Year:  2007        PMID： 17337538      PMCID： PMC1892861          DOI： 10.1128/AEM.02765-06

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  15 in total

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2.  Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: a national reconnaissance.

Authors:  Dana W Kolpin; Edward T Furlong; Michael T Meyer; E Michael Thurman; Steven D Zaugg; Larry B Barber; Herbert T Buxton
Journal:  Environ Sci Technol       Date:  2002-03-15       Impact factor: 9.028

3.  The sequence and crystal structure of the alpha-amino acid ester hydrolase from Xanthomonas citri define a new family of beta-lactam antibiotic acylases.

Authors:  Thomas R M Barends; Jolanda J Polderman-Tijmes; Peter A Jekel; Charles M H Hensgens; Erik J de Vries; Dick B Janssen; Bauke W Dijkstra
Journal:  J Biol Chem       Date:  2003-04-08       Impact factor: 5.157

4.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

Authors:  M M Bradford
Journal:  Anal Biochem       Date:  1976-05-07       Impact factor: 3.365

5.  Identification of the catalytic residues of alpha-amino acid ester hydrolase from Acetobacter turbidans by labeling and site-directed mutagenesis.

Authors:  Jolanda J Polderman-Tijmes; Peter A Jekel; C Margot Jeronimus-Stratingh; Andries P Bruins; Jan-Metske Van Der Laan; Theo Sonke; Dick B Janssen
Journal:  J Biol Chem       Date:  2002-05-14       Impact factor: 5.157

6.  In vitro human metabolism and interactions of repellent N,N-diethyl-m-toluamide.

Authors:  Khawja A Usmani; Randy L Rose; Joyce A Goldstein; Wesley G Taylor; Alan A Brimfield; Ernest Hodgson
Journal:  Drug Metab Dispos       Date:  2002-03       Impact factor: 3.922

7.  Metabolism of toluene and xylenes by Pseudomonas (putida (arvilla) mt-2: evidence for a new function of the TOL plasmid.

Authors:  M J Worsey; P A Williams
Journal:  J Bacteriol       Date:  1975-10       Impact factor: 3.490

8.  Purification and characterization of N,N-dimethylformamidase from Pseudomonas DMF 3/3.

Authors:  H P Schär; W Holzmann; G M Ramos Tombo; O Ghisalba
Journal:  Eur J Biochem       Date:  1986-08-01

Review 9.  DEET: a review and update of safety and risk in the general population.

Authors:  Daniel L Sudakin; Wade R Trevathan
Journal:  J Toxicol Clin Toxicol       Date:  2003

10.  J1 acylase, a glutaryl-7-aminocephalosporanic acid acylase from Bacillus laterosporus J1, is a member of the alpha/beta-hydrolase fold superfamily.

Authors:  Ming-Hon Yau; Jun Wang; Paul W K Tsang; Wing-Ping Fong
Journal:  FEBS Lett       Date:  2006-01-31       Impact factor: 4.124
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  2 in total

1.  N,N-Diethyl-m-Toluamide Exposure at an Environmentally Relevant Concentration Influences River Microbial Community Development.

Authors:  John R Lawrence; Marley J Waiser; George D W Swerhone; Julie L Roy; Armelle Paule; Darren R Korber
Journal:  Environ Toxicol Chem       Date:  2019-09-26       Impact factor: 3.742

2.  Exposure to N,N-diethyl-m-toluamide and cardiovascular diseases in adults.

Authors:  Shiwei Yan; Jianing Wang; Jiaxu Xu; Wenbo Jiang; Menglin Xiong; Ziteng Cao; Yu Wang; Ziqi Wang; Tongfang Zhang; Zheng Wang; Changhao Sun; Shaoying Hou; Wei Wei
Journal:  Front Public Health       Date:  2022-10-03
  2 in total

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