Jian-Hua Wang1, Xiao-Hong He, Rui-Jin Wu, Xiang-Rong Xu. 1. Department of Obstetrics and Gynecology, Women's Hospital, The School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China. wjh421@163.com
Abstract
OBJECTIVE: To study the clinicopathologic characteristics and the treatment means of pregnant women with uterine adenomyoma. DESIGN: Retrospective, consecutive, controlled study. SETTING: University hospital for obstetrics and gynecology. PATIENT(S): Eighteen pregnant women with uterine adenomyoma. INTERVENTION(S): Data collection and statistical analysis. MAIN OUTCOME MEASURE(S): Eighteen pregnant women with uterine adenomyoma were diagnosed by excision of adenomyoma tissue during cesarean section and histopathology. The 18 subjects were retrospectively divided into treatment group (achieving this pregnancy by treatment; 10 cases) and control group (having no difficulty conceiving; 8 cases). The clinicopathologic characteristics and treatment means of the patients were analyzed retrospectively. RESULT(S): The mean volume of uterine adenomyoma in the treatment group was larger than that of the control group. The methods of treating women with uterine adenomyoma-associated infertility include GnRH agonist (GnRH-a: 6 cases), GnRH-a and IVF and embryo transfer (3 cases), and traditional Chinese medicines (1 case). CONCLUSION(S): Severe uterine adenomyoma correlate with infertility in women of childbearing age. GnRH-a is effective in treating women with uterine adenomyoma-associated infertility.
OBJECTIVE: To study the clinicopathologic characteristics and the treatment means of pregnant women with uterine adenomyoma. DESIGN: Retrospective, consecutive, controlled study. SETTING: University hospital for obstetrics and gynecology. PATIENT(S): Eighteen pregnant women with uterine adenomyoma. INTERVENTION(S): Data collection and statistical analysis. MAIN OUTCOME MEASURE(S): Eighteen pregnant women with uterine adenomyoma were diagnosed by excision of adenomyoma tissue during cesarean section and histopathology. The 18 subjects were retrospectively divided into treatment group (achieving this pregnancy by treatment; 10 cases) and control group (having no difficulty conceiving; 8 cases). The clinicopathologic characteristics and treatment means of the patients were analyzed retrospectively. RESULT(S): The mean volume of uterine adenomyoma in the treatment group was larger than that of the control group. The methods of treating women with uterine adenomyoma-associated infertility include GnRH agonist (GnRH-a: 6 cases), GnRH-a and IVF and embryo transfer (3 cases), and traditional Chinese medicines (1 case). CONCLUSION(S): Severe uterine adenomyoma correlate with infertility in women of childbearing age. GnRH-a is effective in treating women with uterine adenomyoma-associated infertility.