Literature DB >> 17336071

I will survive: DNA protection in bacterial spores.

Peter Setlow1.   

Abstract

Dormant spores of Bacillus, Clostridium and related species can survive for years, largely because spore DNA is well protected against damage by many different agents. This DNA protection is partly a result of the high level of Ca(2+)-dipicolinic acid in spores and DNA repair during spore outgrowth, but is primarily caused by the saturation of spore DNA with a group of small, acid-soluble spore proteins (SASP), which are synthesized in the developing spore and then degraded after completion of spore germination. The structure of both DNA and SASP alters upon their association and this causes major changes in the chemical and photochemical reactivity of DNA.

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Year:  2007        PMID: 17336071     DOI: 10.1016/j.tim.2007.02.004

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN: 0966-842X            Impact factor:   17.079


  132 in total

Review 1.  [Coronary heart disease and its differential treatment].

Authors:  M Diewitz
Journal:  Med Welt       Date:  1975-10-24

2.  Evaluation of a stochastic inactivation model for heat-activated spores of Bacillus spp.

Authors:  Maria G Corradini; Mark D Normand; Murray Eisenberg; Micha Peleg
Journal:  Appl Environ Microbiol       Date:  2010-05-07       Impact factor: 4.792

3.  A novel spore protein, ExsM, regulates formation of the exosporium in Bacillus cereus and Bacillus anthracis and affects spore size and shape.

Authors:  Monica M Fazzini; Raymond Schuch; Vincent A Fischetti
Journal:  J Bacteriol       Date:  2010-06-11       Impact factor: 3.490

Review 4.  Exit from dormancy in microbial organisms.

Authors:  Jonathan Dworkin; Ishita M Shah
Journal:  Nat Rev Microbiol       Date:  2010-10-25       Impact factor: 60.633

5.  Effect of a small, acid-soluble spore protein from Clostridium perfringens on the resistance properties of Bacillus subtilis spores.

Authors:  Juan Francisco Leyva-Illades; Barbara Setlow; Mahfuzur R Sarker; Peter Setlow
Journal:  J Bacteriol       Date:  2007-08-31       Impact factor: 3.490

6.  Spore photoproduct lyase catalyzes specific repair of the 5R but not the 5S spore photoproduct.

Authors:  Tilak Chandra; Sunshine C Silver; Egidijus Zilinskas; Eric M Shepard; William E Broderick; Joan B Broderick
Journal:  J Am Chem Soc       Date:  2009-02-25       Impact factor: 15.419

Review 7.  Clostridium difficile spore biology: sporulation, germination, and spore structural proteins.

Authors:  Daniel Paredes-Sabja; Aimee Shen; Joseph A Sorg
Journal:  Trends Microbiol       Date:  2014-05-07       Impact factor: 17.079

8.  An autoinhibitory conformation of the Bacillus subtilis spore coat protein SpoIVA prevents its premature ATP-independent aggregation.

Authors:  Jean-Philippe Castaing; Scarlett Lee; Vivek Anantharaman; Geoffrey E Ravilious; L Aravind; Kumaran S Ramamurthi
Journal:  FEMS Microbiol Lett       Date:  2014-05-20       Impact factor: 2.742

9.  Contributions of four cortex lytic enzymes to germination of Bacillus anthracis spores.

Authors:  Jared D Heffron; Emily A Lambert; Nora Sherry; David L Popham
Journal:  J Bacteriol       Date:  2009-12-04       Impact factor: 3.490

10.  Role of the Nfo and ExoA apurinic/apyrimidinic endonucleases in repair of DNA damage during outgrowth of Bacillus subtilis spores.

Authors:  Juan R Ibarra; Alma D Orozco; Juan A Rojas; Karina López; Peter Setlow; Ronald E Yasbin; Mario Pedraza-Reyes
Journal:  J Bacteriol       Date:  2008-01-18       Impact factor: 3.490

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