Literature DB >> 1733529

Continuous oxygen saturation monitoring following rectal methohexitone induction in paediatric patients.

A L Daniels1, C J Coté, D M Polaner.   

Abstract

Rectal methohexitone has been used to induce anaesthesia in paediatric patients for a number of years. This study was conducted in order to confirm the safety of this method of induction for uncomplicated routine paediatric patients. Children between the ages of six months and six years were considered candidates for induction with methohexitone (10%, 25-30 mg.kg-1). Patients were monitored with a continuous oxygen saturation recording. Forty-nine patients participated in this study and anaesthesia was induced successfully in 44. The mean age of the patients was 2.7 +/- 1.6 yr. The mean weight was 13.8 +/- 4.3 kg and the mean dose of methohexitone for successful induction was 27.0 +/- 3.0 mg.kg-1. Continuous oximeter recordings were available in 31 of the 42 patients who allowed oximeter placement prior to administration of methohexitone. No major desaturation events were noted in any patient. Two brief episodes of desaturation occurred. One with a nadir of 90% which lasted for 45 sec and another with a nadir of 86% which lasted for 26 sec. Both children had their heads flexed over their parents' shoulders at the time of the event resulting in partial airway obstruction. Both of these episodes were the result of upper airway obstruction which was clinically diagnosed by the anesthetist and readily corrected by repositioning the head. This study confirms the efficacy and safety of rectal methohexitone for induction of general anaesthesia in children. Mechanical obstruction of the airway following induction seems to be the most likely cause for oxygen desaturation. Monitoring of pulse oximetry does not appear necessary provided the child is carefully observed for adequacy of air exchange.

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Year:  1992        PMID: 1733529     DOI: 10.1007/BF03008668

Source DB:  PubMed          Journal:  Can J Anaesth        ISSN: 0832-610X            Impact factor:   5.063


  9 in total

1.  SODIUM METHOHEXITAL AS A RECTAL AGENT IN PEDIATRIC ANESTHESIA: A CONTROLLED COMPARISON WITH SODIUM THIAMYLAL.

Authors:  M O ORALLO; K F EATHER
Journal:  Anesth Analg       Date:  1965 Jan-Feb       Impact factor: 5.108

2.  Comparison of two and ten per cent rectal methohexitone for induction of anaesthesia in children.

Authors:  R B Forbes; G E Vandewalker
Journal:  Can J Anaesth       Date:  1988-07       Impact factor: 5.063

3.  Methohexital plasma concentrations in children following rectal administration.

Authors:  L M Liu; P Gaudreault; P A Friedman; N G Goudsouzian; P L Liu
Journal:  Anesthesiology       Date:  1985-05       Impact factor: 7.892

4.  Seizures induced by methohexital.

Authors:  M A Rockoff; N G Goudsouzian
Journal:  Anesthesiology       Date:  1981-04       Impact factor: 7.892

5.  Rectal methohexital premedication in children, a dose-comparison study.

Authors:  L M Liu; N G Goudsouzian; P L Liu
Journal:  Anesthesiology       Date:  1980-10       Impact factor: 7.892

6.  Effects of rectal thiopentone and methohexitone on carbon dioxide tension in infant anaesthesia with spontaneous ventilation.

Authors:  L E Larsson; K Nilsson; S Andreasson; B Ekström-Jodal
Journal:  Acta Anaesthesiol Scand       Date:  1987-04       Impact factor: 2.105

7.  A single-blind study of combined pulse oximetry and capnography in children.

Authors:  C J Coté; N Rolf; L M Liu; N G Goudsouzian; J F Ryan; A Zaslavsky; R Gore; T D Todres; S Vassallo; D Polaner
Journal:  Anesthesiology       Date:  1991-06       Impact factor: 7.892

8.  Effects of dose and concentration of rectal methohexitone for induction of anaesthesia in children.

Authors:  R S Laishley; A C O'Callaghan; J Lerman
Journal:  Can Anaesth Soc J       Date:  1986-07

9.  A single-blind study of pulse oximetry in children.

Authors:  C J Coté; E A Goldstein; M A Coté; D C Hoaglin; J F Ryan
Journal:  Anesthesiology       Date:  1988-02       Impact factor: 7.892

  9 in total
  1 in total

1.  Premedication for ambulatory surgery in preschool children: a comparison of oral midazolam and rectal thiopentone.

Authors:  B Lyons; N Cregg; F Conway; W Casey; P Doherty; K P Moore
Journal:  Can J Anaesth       Date:  1995-06       Impact factor: 5.063

  1 in total

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