Literature DB >> 17334978

Glutamate measurement in Parkinson's disease using MRS at 3 T field strength.

Nils Kickler1, Paul Krack, Valérie Fraix, Jean-François Lebas, Laurent Lamalle, Franck Durif, Alexandre Krainik, Chantal Rémy, Christoph Segebarth, Pierre Pollak.   

Abstract

Loss of nigral dopamine neurons in Parkinson's disease induces abnormal activation of glutamate systems in the basal ganglia. The purpose of this study was to assess these changes in the lentiform nucleus using MRS with optimized glutamate sensitivity (TE-averaged method). Ten patients with Parkinson's disease and 10 healthy controls were examined. Compared with healthy controls, no significant differences in glutamate were measured in patients, but a trend to lower total creatine was observed.

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Year:  2007        PMID： 17334978     DOI： 10.1002/nbm.1141

Source DB:  PubMed          Journal:  NMR Biomed        ISSN： 0952-3480            Impact factor:   4.044


  15 in total

1.  Phase-adjusted echo time (PATE)-averaging 1 H MRS: application for improved glutamine quantification at 2.89 T.

Authors:  Andrew P Prescot; Todd Richards; Stephen R Dager; Changho Choi; Perry F Renshaw
Journal:  NMR Biomed       Date:  2012-03-12       Impact factor: 4.044

Review 2.  Magnetic resonance spectroscopy to assess neuroinflammation and neuropathic pain.

Authors:  Linda Chang; Sody M Munsaka; Stephanie Kraft-Terry; Thomas Ernst
Journal:  J Neuroimmune Pharmacol       Date:  2013-05-12       Impact factor: 4.147

3.  Comparison of spectral fitting methods for overlapping J-coupled metabolite resonances.

Authors:  A Gonenc; V Govind; S Sheriff; A A Maudsley
Journal:  Magn Reson Med       Date:  2010-09       Impact factor: 4.668

4.  Proton MR spectroscopy-detectable major neurotransmitters of the brain: biology and possible clinical applications.

Authors:  N Agarwal; P F Renshaw
Journal:  AJNR Am J Neuroradiol       Date:  2011-12-29       Impact factor: 3.825

5.  Lower glutamate levels in rostral anterior cingulate of chronic cocaine users - A (1)H-MRS study using TE-averaged PRESS at 3 T with an optimized quantification strategy.

Authors:  Shaolin Yang; Betty Jo Salmeron; Thomas J Ross; Zheng-Xiong Xi; Elliot A Stein; Yihong Yang
Journal:  Psychiatry Res       Date:  2009-11-10       Impact factor: 3.222

6.  Metabolic Abnormalities in Abstinent Methamphetamine Dependent Subjects.

Authors:  Napapon Sailasuta; Osama Abulseoud; Martha Hernandez; Poone Haghani; Brian D Ross
Journal:  Subst Abuse       Date:  2010-04-07

7.  Effects of age and sex on brain glutamate and other metabolites.

Authors:  Linda Chang; Caroline S Jiang; Thomas Ernst
Journal:  Magn Reson Imaging       Date:  2008-08-06       Impact factor: 2.546

8.  Inhibitory motor dysfunction in parkinson's disease subtypes.

Authors:  Tao Gong; Yuanyuan Xiang; Muhammad G Saleh; Fei Gao; Weibo Chen; Richard A E Edden; Guangbin Wang
Journal:  J Magn Reson Imaging       Date:  2017-09-27       Impact factor: 4.813

9.  Morphological and metabolic changes in the nigro-striatal pathway of synthetic proteasome inhibitor (PSI)-treated rats: a MRI and MRS study.

Authors:  Stefano Delli Pizzi; Cosmo Rossi; Vincenzo Di Matteo; Ennio Esposito; Simone Guarnieri; Maria Addolorata Mariggiò; Raffaella Franciotti; Massimo Caulo; Astrid Thomas; Marco Onofrj; Armando Tartaro; Laura Bonanni
Journal:  PLoS One       Date:  2013-02-19       Impact factor: 3.240

10.  Elevated pontine and putamenal GABA levels in mild-moderate Parkinson disease detected by 7 tesla proton MRS.

Authors:  Uzay E Emir; Paul J Tuite; Gülin Öz
Journal:  PLoS One       Date:  2012-01-25       Impact factor: 3.240
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