Literature DB >> 1733459

A report of two cases of chronic serious manganese poisoning treated with sodium para-aminosalicylic acid.

S Q Ky1, H S Deng, P Y Xie, W Hu.   

Abstract

Two cases of chronic manganese poisoning were treated with sodium para-aminosalicylic acid (PAS-Na; 6 g/day in 500 ml of 10% glucose solution by intravenous drip). The results indicated that one had been clinically cured and that the other had obviously improved in clinical symptoms and signs. Thus PAS-Na appears to be an effective drug for treatment of serious chronic manganese poisoning.

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Year:  1992        PMID： 1733459      PMCID： PMC1039237          DOI： 10.1136/oem.49.1.66

Source DB:  PubMed          Journal:  Br J Ind Med        ISSN： 0007-1072


  19 in total

Review 1.  Manganese and its role in Parkinson's disease: from transport to neuropathology.

Authors:  Michael Aschner; Keith M Erikson; Elena Herrero Hernández; Elena Herrero Hernández; Ronald Tjalkens
Journal:  Neuromolecular Med       Date:  2009       Impact factor: 3.843

2.  Manganese exposure exacerbates progressive motor deficits and neurodegeneration in the MitoPark mouse model of Parkinson's disease: Relevance to gene and environment interactions in metal neurotoxicity.

Authors:  Monica R Langley; Shivani Ghaisas; Muhammet Ay; Jie Luo; Bharathi N Palanisamy; Huajun Jin; Vellareddy Anantharam; Arthi Kanthasamy; Anumantha G Kanthasamy
Journal:  Neurotoxicology       Date:  2017-06-20       Impact factor: 4.294

3.  Novel founder intronic variant in SLC39A14 in two families causing Manganism and potential treatment strategies.

Authors:  Lance H Rodan; Marissa Hauptman; Alissa M D'Gama; Anita E Qualls; Siqi Cao; Karin Tuschl; Fatma Al-Jasmi; Jozef Hertecant; Susan J Hayflick; Marianne Wessling-Resnick; Edward T Yang; Gerard T Berry; Andrea Gropman; Alan D Woolf; Pankaj B Agrawal
Journal:  Mol Genet Metab       Date:  2018-04-06       Impact factor: 4.797

4.  Brain regional pharmacokinetics of p-aminosalicylic acid and its N-acetylated metabolite: effectiveness in chelating brain manganese.

Authors:  Lan Hong; Wendy Jiang; Hao Pan; Yueming Jiang; Su Zeng; Wei Zheng
Journal:  Drug Metab Dispos       Date:  2011-07-18       Impact factor: 3.922

5.  Sodium P-aminosalicylic Acid Attenuates Manganese-Induced Neuroinflammation in BV2 Microglia by Modulating NF-κB Pathway.

Authors:  Junyan Li; Yue Deng; Dongjie Peng; Lin Zhao; Yuanyuan Fang; Xiaojuan Zhu; Shaojun Li; Michael Aschner; Shiyan Ou; Yueming Jiang
Journal:  Biol Trace Elem Res       Date:  2021-01-14       Impact factor: 3.738

6.  Effective treatment of manganese-induced occupational Parkinsonism with p-aminosalicylic acid: a case of 17-year follow-up study.

Authors:  Yue-Ming Jiang; Xue-An Mo; Feng-Qi Du; Xue Fu; Xia-Yan Zhu; Hong-Yu Gao; Jin-Lan Xie; Feng-Ling Liao; Enrico Pira; Wei Zheng
Journal:  J Occup Environ Med       Date:  2006-06       Impact factor: 2.162

7.  Neuroprotective and Therapeutic Strategies for Manganese-Induced Neurotoxicity.

Authors:  A P Marreilha Dos Santos; V Andrade; M Aschner
Journal:  Clin Pharmacol Transl Med       Date:  2017-05-26

8.  HPLC analysis of para-aminosalicylic acid and its metabolite in plasma, cerebrospinal fluid and brain tissues.

Authors:  Lan Hong; Wendy Jiang; Wei Zheng; Su Zeng
Journal:  J Pharm Biomed Anal       Date:  2010-11-27       Impact factor: 3.935

9.  Effects of p-Aminosalicylic acid on the neurotoxicity of manganese on the dopaminergic innervation of the cilia of the lateral cells of the gill of the bivalve mollusc, Crassostrea virginica.

Authors:  Michael Nelson; Turkesha Huggins; Roshney Licorish; Margaret A Carroll; Edward J Catapane
Journal:  Comp Biochem Physiol C Toxicol Pharmacol       Date:  2010-03       Impact factor: 3.228

Review 10.  Manganese: recent advances in understanding its transport and neurotoxicity.

Authors:  Michael Aschner; Tomás R Guilarte; Jay S Schneider; Wei Zheng
Journal:  Toxicol Appl Pharmacol       Date:  2007-03-12       Impact factor: 4.219
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