Literature DB >> 17333036

[Lymphadenectomy with tumors of the lower gastrointestinal tract].

W Hohenberger1, S Merkel, K Weber.   

Abstract

For advanced adenocarcinomas, which are the most frequent tumours of the lower GI tract, the concept of radical lymphnode dissection is well accepted. The quality of lymphadenectomy for these malignancies has a strong effect on cancer-related survival. Based upon a strict quality control program with outcome evaluated according to internal results, the technique and extent of lymph node dissection have been continuously developed over the last three decades. These are described in detail, including instructive pictures to clarify the surgical steps needed. Apart from multivisceral resection in far advanced cases, which still have a chance of cure if adequate guidelines are followed, two additional steps in the so-called radical surgical treatment of these tumours are prerequisites for cure. The first is complete mobilisation of the intestine involving complete mesocolic excision with complete retention of the visceral fascia and covering potential lymph node metastases and extranodal spread on the intestinal side. The second step is the central tying of the tumor's supplying vessels. Following these rules and with no adjuvant systemic treatment, 5-year survival figures of 80% can be reached, even for UICC stage III disease.

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Year:  2007        PMID: 17333036     DOI: 10.1007/s00104-007-1311-y

Source DB:  PubMed          Journal:  Chirurg        ISSN: 0009-4722            Impact factor:   0.955


  33 in total

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Review 8.  [Local therapy principles in rectal carcinoma].

Authors:  K E Matzel; S Merkel; W Hohenberger
Journal:  Chirurg       Date:  2003-10       Impact factor: 0.955

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Authors:  W Hohenberger; C H Schick; J Göhl
Journal:  Langenbecks Arch Surg       Date:  1998-12       Impact factor: 3.445

10.  Prognostic factors of primary small bowel adenocarcinoma: univariate and multivariate analysis.

Authors:  Ting-Jung Wu; Chun-Nan Yeh; Tzu-Chieh Chao; Yi-Yin Jan; Miin-Fu Chen
Journal:  World J Surg       Date:  2006-03       Impact factor: 3.352

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  13 in total

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Review 2.  Complete mesocolic excision and D3 lymphadenectomy with central vascular ligation in right-sided colon cancer: a systematic review of postoperative outcomes, tumor recurrence and overall survival.

Authors:  Gennaro Mazzarella; Edoardo Maria Muttillo; Biagio Picardi; Stefano Rossi; Irnerio Angelo Muttillo
Journal:  Surg Endosc       Date:  2021-05-11       Impact factor: 4.584

3.  Despite aggressive histopathology survival is not impaired in young patients with colorectal cancer : CRC in patients under 50 years of age.

Authors:  Vera Simone Schellerer; Susanne Merkel; Silke Christiane Schumann; Anne Schlabrakowski; Thomas Förtsch; Claus Schildberg; Werner Hohenberger; Roland Siegfried Croner
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4.  [Tumors of the lower gastrointestinal tract : Indication and extent of lymph node dissection].

Authors:  S Merkel; K Weber; A Perrakis; J Göhl; W Hohenberger
Journal:  Chirurg       Date:  2010-02       Impact factor: 0.955

5.  Laparoscopic Colorectal Surgery for Cancer: What Is the Role of Complete Mesocolic Excision and Splenic Flexure Mobilization?

Authors:  Rosario Vecchio; Salvatore Marchese; Eva Intagliata
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Review 6.  Laparoscopic complete mesocolic excision: West meets East.

Authors:  Carina F K Chow; Seon Hahn Kim
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Review 7.  [Lymph node dissection for carcinomas of the lower gastrointestinal tract. What is evidence-based?].

Authors:  W Hohenberger; P Lux; S Merkel; K Weber
Journal:  Chirurg       Date:  2011-12       Impact factor: 0.955

8.  Is complete mesocolic excision with central vascular ligation safe and effective in the surgical treatment of right-sided colon cancers? A prospective study.

Authors:  Gennaro Galizia; Eva Lieto; Ferdinando De Vita; Francesca Ferraraccio; Anna Zamboli; Andrea Mabilia; Annamaria Auricchio; Paolo Castellano; Vincenzo Napolitano; Michele Orditura
Journal:  Int J Colorectal Dis       Date:  2013-08-28       Impact factor: 2.571

9.  Is there a disadvantage to radical lymph node dissection in colon cancer?

Authors:  K Weber; S Merkel; A Perrakis; W Hohenberger
Journal:  Int J Colorectal Dis       Date:  2012-09-02       Impact factor: 2.571

Review 10.  Complete mesocolic excision for colon cancer: is it worth it?

Authors:  Frederick H Koh; Ker-Kan Tan
Journal:  J Gastrointest Oncol       Date:  2019-12
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