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Literature DB >> 17332078

Epigenetic control of hematopoietic stem cell aging the case of Ezh2.

Abstract

Hematopoietic stem cells have potent, but not unlimited, selfrenewal potential. The mechanisms that restrict selfrenewal are likely to play a role during aging. Recent data suggest that the regulation of histone modifications by Polycomb group genes may be of crucial relevance to balance selfrenewal and aging. We provide evidence for the involvement of one of these Polycomb group genes, Ezh2, in aging of the hematopoietic stem cell system.

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Year: 2007 PMID： 17332078 DOI： 10.1196/annals.1392.008

Source DB: PubMed Journal: Ann N Y Acad Sci ISSN： 0077-8923 Impact factor: 5.691

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Cited

13 in total

1. MicroRNA-1297 regulates hepatocellular carcinoma cell proliferation and apoptosis by targeting EZH2.

Authors: Fenghua Liu; Yukai He; Ronghua Shu; Sikui Wang
Journal: Int J Clin Exp Pathol Date: 2015-05-01

2. Inhibition of EZH2 reverses chemotherapeutic drug TMZ chemosensitivity in glioblastoma.

Authors: Tian-Yu Fan; Hai Wang; Peng Xiang; Ya-Wei Liu; He-Zhen Li; Bing-Xi Lei; Meng Yu; Song-Tao Qi
Journal: Int J Clin Exp Pathol Date: 2014-09-15

3. The roles of EZH2 in cell lineage commitment.

Authors: Ruey-Hwang Chou; Yung-Luen Yu; Mien-Chie Hung
Journal: Am J Transl Res Date: 2011-04-21 Impact factor: 4.060

4. Steroidogenic differentiation and PKA signaling are programmed by histone methyltransferase EZH2 in the adrenal cortex.

Authors: Mickael Mathieu; Coralie Drelon; Stéphanie Rodriguez; Houda Tabbal; Amandine Septier; Christelle Damon-Soubeyrand; Typhanie Dumontet; Annabel Berthon; Isabelle Sahut-Barnola; Cyril Djari; Marie Batisse-Lignier; Jean-Christophe Pointud; Damien Richard; Gwenneg Kerdivel; Marie-Ange Calméjane; Valentina Boeva; Igor Tauveron; Anne-Marie Lefrançois-Martinez; Antoine Martinez; Pierre Val
Journal: Proc Natl Acad Sci U S A Date: 2018-12-12 Impact factor: 11.205

5. Cross talk between microRNA and epigenetic regulation in adult neurogenesis.

Authors: Keith E Szulwach; Xuekun Li; Richard D Smrt; Yujing Li; Yuping Luo; Li Lin; Nicholas J Santistevan; Wendi Li; Xinyu Zhao; Peng Jin
Journal: J Cell Biol Date: 2010-04-05 Impact factor: 10.539

6. Nanog reverses the effects of organismal aging on mesenchymal stem cell proliferation and myogenic differentiation potential.

Authors: Juhee Han; Panagiotis Mistriotis; Pedro Lei; Dan Wang; Song Liu; Stelios T Andreadis
Journal: Stem Cells Date: 2012-12 Impact factor: 6.277

Epigenetic control of hematopoietic stem cell aging the case of Ezh2.

1. MicroRNA-1297 regulates hepatocellular carcinoma cell proliferation and apoptosis by targeting EZH2.

2. Inhibition of EZH2 reverses chemotherapeutic drug TMZ chemosensitivity in glioblastoma.

3. The roles of EZH2 in cell lineage commitment.

4. Steroidogenic differentiation and PKA signaling are programmed by histone methyltransferase EZH2 in the adrenal cortex.

5. Cross talk between microRNA and epigenetic regulation in adult neurogenesis.

6. Nanog reverses the effects of organismal aging on mesenchymal stem cell proliferation and myogenic differentiation potential.

7. Postnatal development- and age-related changes in DNA-methylation patterns in the human genome.

Review 8. EZH2 in normal and malignant hematopoiesis.

9. Promotion of glioblastoma cell motility by enhancer of zeste homolog 2 (EZH2) is mediated by AXL receptor kinase.

10. Aging and replicative senescence have related effects on human stem and progenitor cells.