BACKGROUND: Obesity affects more than 30% of the U.S. population and is associated with the development of life-threatening complications. Numerous therapeutic approaches to the problem have been advocated, including low-calorie diets, anoretic drugs, behavior modifications, and exercise therapy. The only treatment proven to be effective in the long-term management of morbid obesity is surgical intervention. Complications of bariatric surgery include stomal stenosis and/or ulcer and stomal dilation (secondary to overeating). The latter complication can result in a gain of previously lost weight. OBJECTIVE: To determine the effect of endoscopic injection by using a sclerosant (sodium morrhuate) to induce stomal stenosis in patients who present with stomal dilatation complicated by weight gain. DESIGN: Bariatric patients with a large gastric stoma were treated with sodium morrhuate stomal injection. Diameters of the stoma were followed at repeat endoscopy. Weight loss at scheduled clinic visits were compared with pretherapy weights. PATIENTS: Twenty-eight patients (10 men, 18 women; age range, 27-58 years), after bariatric surgery with GI bypass, were referred with weight gain after initial weight loss. Weight gain was believed to be the result of a large gastric stoma. INTERVENTIONS: Treatment included injection of sodium morrhuate (1-2 mL circumferentially) surrounding the stoma. A total of 1 to 3 injection sessions were performed in an attempt to achieve a stoma diameter of 1.2 cm or smaller. MAIN OUTCOME MEASUREMENTS: Treatment success was defined as a decrease of stoma size to <or=12 mm and weight loss >or=75% of the weight the patient gained after establishing a steady state post bariatric surgery weight. RESULTS: A total of 2.3 injection sessions were performed. Successful endotherapy was achieved in 18 of 28 patients (64%). One patient developed symptoms of stomal stenosis, which required 2 separate balloon dilating sessions. No other complications were encountered. LIMITATIONS: Retrospective case series. CONCLUSIONS: Endoscopic injection of sodium morrhuate surrounding the dilated gastric stoma complicating bariatric surgery appears to be a successful, less-invasive therapeutic alternative to surgical revision.
BACKGROUND:Obesity affects more than 30% of the U.S. population and is associated with the development of life-threatening complications. Numerous therapeutic approaches to the problem have been advocated, including low-calorie diets, anoretic drugs, behavior modifications, and exercise therapy. The only treatment proven to be effective in the long-term management of morbid obesity is surgical intervention. Complications of bariatric surgery include stomal stenosis and/or ulcer and stomal dilation (secondary to overeating). The latter complication can result in a gain of previously lost weight. OBJECTIVE: To determine the effect of endoscopic injection by using a sclerosant (sodium morrhuate) to induce stomal stenosis in patients who present with stomal dilatation complicated by weight gain. DESIGN: Bariatric patients with a large gastric stoma were treated with sodium morrhuate stomal injection. Diameters of the stoma were followed at repeat endoscopy. Weight loss at scheduled clinic visits were compared with pretherapy weights. PATIENTS: Twenty-eight patients (10 men, 18 women; age range, 27-58 years), after bariatric surgery with GI bypass, were referred with weight gain after initial weight loss. Weight gain was believed to be the result of a large gastric stoma. INTERVENTIONS: Treatment included injection of sodium morrhuate (1-2 mL circumferentially) surrounding the stoma. A total of 1 to 3 injection sessions were performed in an attempt to achieve a stoma diameter of 1.2 cm or smaller. MAIN OUTCOME MEASUREMENTS: Treatment success was defined as a decrease of stoma size to <or=12 mm and weight loss >or=75% of the weight the patient gained after establishing a steady state post bariatric surgery weight. RESULTS: A total of 2.3 injection sessions were performed. Successful endotherapy was achieved in 18 of 28 patients (64%). One patient developed symptoms of stomal stenosis, which required 2 separate balloon dilating sessions. No other complications were encountered. LIMITATIONS: Retrospective case series. CONCLUSIONS: Endoscopic injection of sodium morrhuate surrounding the dilated gastric stoma complicating bariatric surgery appears to be a successful, less-invasive therapeutic alternative to surgical revision.
Authors: Shahzeer Karmali; Balpreet Brar; Xinzhe Shi; Arya M Sharma; Christopher de Gara; Daniel W Birch Journal: Obes Surg Date: 2013-11 Impact factor: 4.129
Authors: Hideharu Shimizu; Shohrat Annaberdyev; Isaac Motamarry; Matthew Kroh; Philip R Schauer; Stacy A Brethauer Journal: Obes Surg Date: 2013-11 Impact factor: 4.129
Authors: Barham K Abu Dayyeh; Pichamol Jirapinyo; Zachary Weitzner; Charlotte Barker; Michael S Flicker; David B Lautz; Christopher C Thompson Journal: Gastrointest Endosc Date: 2012-08 Impact factor: 9.427
Authors: Lava Y Patel; Brittany Lapin; Craig S Brown; Thomas Stringer; Matthew E Gitelis; John G Linn; Woody E Denham; Elizabeth Farwell; Stephen Haggerty; Michael B Ujiki Journal: Surg Endosc Date: 2016-10-17 Impact factor: 4.584