Literature DB >> 17331492

Grading of renal cell carcinoma by 3D morphological analysis of cell nuclei.

Hyun-Ju Choi1, Heung-Kook Choi.   

Abstract

This study attempted to develop a method for 3D visualization and quantitative analysis of cell nuclei for renal cell carcinoma (RCC) grading and evaluated the feasibility of such quantitative analysis. We compared the correct classification rate (CCR) for each of the classifiers based on the 2D features of cell nuclei (diameter, area, perimeter, and circularity) and the 3D features of cell nuclei (volume, surface area, and spherical shape factor). The results showed that the classifier using the 3D features provided better results for grading. Our method could overcome the limitations inherent in 2D analysis and could improve the accuracy and reproducibility of quantification of cell nuclei.

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Mesh：

Year:  2007        PMID： 17331492     DOI： 10.1016/j.compbiomed.2006.12.008

Source DB:  PubMed          Journal:  Comput Biol Med        ISSN： 0010-4825            Impact factor:   4.589


  5 in total

1.  Automated quantification of DNA demethylation effects in cells via 3D mapping of nuclear signatures and population homogeneity assessment.

Authors:  Arkadiusz Gertych; Kolja A Wawrowsky; Erik Lindsley; Eugene Vishnevsky; Daniel L Farkas; Jian Tajbakhsh
Journal:  Cytometry A       Date:  2009-07       Impact factor: 4.355

2.  3D texture analysis in renal cell carcinoma tissue image grading.

Authors:  Tae-Yun Kim; Nam-Hoon Cho; Goo-Bo Jeong; Ewert Bengtsson; Heung-Kook Choi
Journal:  Comput Math Methods Med       Date:  2014-10-09       Impact factor: 2.238

3.  Histological image classification using biologically interpretable shape-based features.

Authors:  Sonal Kothari; John H Phan; Andrew N Young; May D Wang
Journal:  BMC Med Imaging       Date:  2013-03-13       Impact factor: 1.930

4.  3D Shape Modeling for Cell Nuclear Morphological Analysis and Classification.

Authors:  Alexandr A Kalinin; Ari Allyn-Feuer; Alex Ade; Gordon-Victor Fon; Walter Meixner; David Dilworth; Syed S Husain; Jeffrey R de Wet; Gerald A Higgins; Gen Zheng; Amy Creekmore; John W Wiley; James E Verdone; Robert W Veltri; Kenneth J Pienta; Donald S Coffey; Brian D Athey; Ivo D Dinov
Journal:  Sci Rep       Date:  2018-09-12       Impact factor: 4.379

5.  Valproic acid-induced changes of 4D nuclear morphology in astrocyte cells.

Authors:  Alexandr A Kalinin; Xinhai Hou; Alex S Ade; Gordon-Victor Fon; Walter Meixner; Gerald A Higgins; Jonathan Z Sexton; Xiang Wan; Ivo D Dinov; Matthew J O'Meara; Brian D Athey
Journal:  Mol Biol Cell       Date:  2021-04-28       Impact factor: 4.138
  5 in total

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