Literature DB >> 1733110

Myb protein binds to multiple sites in the human T cell lymphotropic virus type 1 long terminal repeat and transactivates LTR-mediated expression.

R Bosselut1, F Lim, P C Romond, J Frampton, J Brady, J Ghysdael.   

Abstract

The members of the c-myb proto-oncogene family encode sequence-specific transcriptional activators. In T cells, expression of c-myb and the related B-myb gene is induced following mitogenic stimulation. Using a purified recombinant protein, we report here that the human T cell lymphotropic virus type 1 (HTLV-1) LTR contains six specific binding sites for Myb. We also show that HTLV-1 LTR chloramphenicol acetyl transferase reporter plasmids are specifically transactivated by c-Myb. These data suggest a role for members of the Myb family as a link between transcriptional activation of the HTLV-1 LTR and T cell activation events.

Entities:  

Mesh：

Substances：

Year:  1992        PMID： 1733110     DOI： 10.1016/0042-6822(92)90044-p

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  19 in total

1.  ALY is a common coactivator of RUNX1 and c-Myb on the type B leukemogenic virus enhancer.

Authors:  Jennifer A Mertz; Ryuji Kobayashi; Jaquelin P Dudley
Journal:  J Virol       Date:  2007-01-17       Impact factor: 5.103

2.  Transcriptional activation of the human T-lymphotropic virus type I long terminal repeat by functional interaction of Tax1 and Ets1.

Authors:  S D Gitlin; J Dittmer; R C Shin; J N Brady
Journal:  J Virol       Date:  1993-12       Impact factor: 5.103

3.  T-cell receptor/CD28 engagement when combined with prostaglandin E2 treatment leads to potent activation of human T-cell leukemia virus type 1.

Authors:  Nancy Dumais; Marie-Eve Paré; Simon Mercier; Salim Bounou; Susan J Marriot; Benoit Barbeau; Michel J Tremblay
Journal:  J Virol       Date:  2003-10       Impact factor: 5.103

4.  Activation of human T-cell leukemia virus type 1 tax gene expression in chronically infected T cells.

Authors:  H C Lin; C S Dezzutti; R B Lal; A B Rabson
Journal:  J Virol       Date:  1998-07       Impact factor: 5.103

5.  Activation of the human T-cell leukemia virus type 1 long terminal repeat by the ternary complex factor Elk-1.

Authors:  Heather Y Winter; Tajhal Dayaram; Susan J Marriott
Journal:  J Virol       Date:  2007-09-26       Impact factor: 5.103

6.  A new regulatory element that augments the Tax-dependent enhancer of human T-cell leukemia virus type 1 and cloning of cDNAs encoding its binding proteins.

Authors:  A Tanimura; H Teshima; J Fujisawa; M Yoshida
Journal:  J Virol       Date:  1993-09       Impact factor: 5.103

7.  Sequences downstream of the RNA initiation site regulate human T-cell lymphotropic virus type I basal gene expression.

Authors:  F Kashanchi; J F Duvall; P F Lindholm; M F Radonovich; J N Brady
Journal:  J Virol       Date:  1993-05       Impact factor: 5.103

8.  Involvement of transcription factor YB-1 in human T-cell lymphotropic virus type I basal gene expression.

Authors:  F Kashanchi; J F Duvall; J Dittmer; A Mireskandari; R L Reid; S D Gitlin; J N Brady
Journal:  J Virol       Date:  1994-01       Impact factor: 5.103

9.  Identification of alternatively spliced mRNAs encoding potential new regulatory proteins in cattle infected with bovine leukemia virus.

Authors:  S Alexandersen; S Carpenter; J Christensen; T Storgaard; B Viuff; Y Wannemuehler; J Belousov; J A Roth
Journal:  J Virol       Date:  1993-01       Impact factor: 5.103

10.  Ancient, independent evolution and distinct molecular features of the novel human T-lymphotropic virus type 4.

Authors:  William M Switzer; Marco Salemi; Shoukat H Qari; Hongwei Jia; Rebecca R Gray; Aris Katzourakis; Susan J Marriott; Kendle N Pryor; Nathan D Wolfe; Donald S Burke; Thomas M Folks; Walid Heneine
Journal:  Retrovirology       Date:  2009-02-02       Impact factor: 4.602
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.