Literature DB >> 17330904

3-hydroxy-3-methylglutaryl-CoA-like synthases direct the formation of methyl and ethyl side groups in the biosynthesis of the antibiotic myxovirescin A.

Vesna Simunovic1, Rolf Müller.   

Abstract

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Year:  2007        PMID： 17330904     DOI： 10.1002/cbic.200700017

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


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  8 in total

1.  Polyketide β-branching in bryostatin biosynthesis: identification of surrogate acetyl-ACP donors for BryR, an HMG-ACP synthase.

Authors:  Tonia J Buchholz; Christopher M Rath; Nicole B Lopanik; Noah P Gardner; Kristina Håkansson; David H Sherman
Journal:  Chem Biol       Date:  2010-10-29

2.  Incorporation of nonmethyl branches by isoprenoid-like logic: multiple beta-alkylation events in the biosynthesis of myxovirescin A1.

Authors:  Christopher T Calderone; David F Iwig; Pieter C Dorrestein; Neil L Kelleher; Christopher T Walsh
Journal:  Chem Biol       Date:  2007-07

3.  Characterization of the lnmKLM genes unveiling key intermediates for β-alkylation in leinamycin biosynthesis.

Authors:  Yong Huang; Sheng-Xiong Huang; Jianhua Ju; Gongli Tang; Tao Liu; Ben Shen
Journal:  Org Lett       Date:  2010-12-30       Impact factor: 6.005

4.  Myxobacterium-produced antibiotic TA (myxovirescin) inhibits type II signal peptidase.

Authors:  Yao Xiao; Klaus Gerth; Rolf Müller; Daniel Wall
Journal:  Antimicrob Agents Chemother       Date:  2012-01-09       Impact factor: 5.191

5.  Structure of the bifunctional acyltransferase/decarboxylase LnmK from the leinamycin biosynthetic pathway revealing novel activity for a double-hot-dog fold.

Authors:  Jeremy R Lohman; Craig A Bingman; George N Phillips; Ben Shen
Journal:  Biochemistry       Date:  2013-01-24       Impact factor: 3.162

6.  Bifunctional acyltransferase/decarboxylase LnmK as the missing link for beta-alkylation in polyketide biosynthesis.

Authors:  Tao Liu; Yong Huang; Ben Shen
Journal:  J Am Chem Soc       Date:  2009-05-27       Impact factor: 15.419

7.  The Discovery of Actinospene, a New Polyene Macrolide with Broad Activity against Plant Fungal Pathogens and Pathogenic Yeasts.

Authors:  Ying Tang; Cuiyang Zhang; Tianqi Cui; Ping Lei; Zhaohui Guo; Hailong Wang; Qingshu Liu
Journal:  Molecules       Date:  2021-11-20       Impact factor: 4.411

Review 8.  Research Progress in the Biosynthetic Mechanisms of Marine Polyether Toxins.

Authors:  Xiukun Wan; Ge Yao; Yanli Liu; Jisheng Chen; Hui Jiang
Journal:  Mar Drugs       Date:  2019-10-22       Impact factor: 5.118
  8 in total

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