Nadia Micali1, Emily Simonoff, Janet Treasure. 1. Department of Child and Adolescent Psychiatry, Institute of Psychiatry, King's College London, Box 085, De Crespigny Park, London SE5 8AF, UK. N.Micali@iop.kcl.ac.uk
Abstract
BACKGROUND: Low birth weight, prematurity and higher miscarriage rates have previously been reported in women with eating disorders. AIMS: To determine whether women with a history of eating disorders are at higher risk of major adverse perinatal outcomes. METHODS: Adjusted birth weight, preterm delivery and miscarriage history were compared in those with a history of eating disorders (anorexia nervosa (n=171), bulimia nervosa (n=199) and both (n=82)) and those with other (n=1166) and no psychiatric disorders (n=10 636) in a longitudinal cohort study. RESULTS: The group with bulimia nervosa had significantly higher rates of past miscarriages (relative risk ratio 2.0, P=0.01) and the group with anorexia nervosa delivered babies of significantly lower birth weight than the general population (P=0.01), which was mainly explained by lower pre-pregnancy body mass index. Preterm delivery rates were comparable across groups. CONCLUSIONS: Women with a history of eating disorders are at higher risk of major adverse obstetric outcomes. Antenatal services should be aware of this higher risk.
BACKGROUND: Low birth weight, prematurity and higher miscarriage rates have previously been reported in women with eating disorders. AIMS: To determine whether women with a history of eating disorders are at higher risk of major adverse perinatal outcomes. METHODS: Adjusted birth weight, preterm delivery and miscarriage history were compared in those with a history of eating disorders (anorexia nervosa (n=171), bulimia nervosa (n=199) and both (n=82)) and those with other (n=1166) and no psychiatric disorders (n=10 636) in a longitudinal cohort study. RESULTS: The group with bulimia nervosa had significantly higher rates of past miscarriages (relative risk ratio 2.0, P=0.01) and the group with anorexia nervosa delivered babies of significantly lower birth weight than the general population (P=0.01), which was mainly explained by lower pre-pregnancy body mass index. Preterm delivery rates were comparable across groups. CONCLUSIONS: Women with a history of eating disorders are at higher risk of major adverse obstetric outcomes. Antenatal services should be aware of this higher risk.
Authors: H J Watson; A Von Holle; R M Hamer; C Knoph Berg; L Torgersen; P Magnus; C Stoltenberg; P Sullivan; T Reichborn-Kjennerud; C M Bulik Journal: Psychol Med Date: 2012-11-20 Impact factor: 7.723
Authors: Hunna J Watson; Ann Von Holle; Cecilie Knoph; Robert M Hamer; Leila Torgersen; Ted Reichborn-Kjennerud; Camilla Stoltenberg; Per Magnus; Cynthia M Bulik Journal: Int J Eat Disord Date: 2014-10-27 Impact factor: 4.861
Authors: Katie M O'Brien; Denis R Whelan; Dale P Sandler; Clarice R Weinberg Journal: Cancer Epidemiol Biomarkers Prev Date: 2016-10-18 Impact factor: 4.254