OBJECTIVE: Auditory P300 has been reported to be abnormal in demented patients with Parkinson's disease. However, it is still controversial which factors in Parkinson's disease influence P300 parameters. METHODS: Forty patients with Parkinson's disease were included. Patients were divided into two groups: patients with dementia (PDD) and without dementia (PDND). An 'odd-ball' paradigm was used for auditory event-related potentials. RESULTS: P300 latency was markedly delayed in PDD patients. Age and DRS1 (attention) were the most important factors influencing P300 latency. CONCLUSIONS: Although there have been reports of P300 in the past, its abnormalities reflect the deficit of attention in Parkinson's disease.
OBJECTIVE: Auditory P300 has been reported to be abnormal in demented patients with Parkinson's disease. However, it is still controversial which factors in Parkinson's disease influence P300 parameters. METHODS: Forty patients with Parkinson's disease were included. Patients were divided into two groups: patients with dementia (PDD) and without dementia (PDND). An 'odd-ball' paradigm was used for auditory event-related potentials. RESULTS:P300 latency was markedly delayed in PDDpatients. Age and DRS1 (attention) were the most important factors influencing P300 latency. CONCLUSIONS: Although there have been reports of P300 in the past, its abnormalities reflect the deficit of attention in Parkinson's disease.
Authors: Ali Soliman Shalash; Dalia Mohamed Hassan; Hanan Hani Elrassas; Mohamed Mosaad Salama; Edna Méndez-Hernández; José M Salas-Pacheco; Oscar Arias-Carrión Journal: Front Neurol Date: 2017-02-27 Impact factor: 4.003
Authors: Walter Di Iorio; Alessandro Ciarimboli; Giorgio Ferriero; Michele Feleppa; Luigi Baratto; Giuseppe Matarazzo; Giovanni Gentile; Stefano Masiero; Patrizio Sale Journal: Diseases Date: 2018-07-04