| Literature DB >> 17328238 |
Van-Thoai Pham1, Jae-Eun Joo, Yong-Shou Tian, Chang-Young Oh, Won-Hun Ham.
Abstract
In this study, we explored a convenient and concise route for synthesis of D-erythro-sphingosine 1 from commercially available and cheap L-serine. The key steps are simple preparation of amino ketone 5 from Weinreb amide 3 and high diastereoselective reduction of amino ketone 5 to give the natural erythro-(anti-) isomer.Entities:
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Year: 2007 PMID： 17328238 DOI： 10.1007/bf02977774
Source DB: PubMed Journal: Arch Pharm Res ISSN： 0253-6269 Impact factor: 4.946