AIM: The purpose of this study is to present data on a series of peripheral odontogenic fibroma, WHO (World Health Organization)-type (POF), in Brazilians and to compare the results with previously reported studies. METHODS: The study sample was made from the number of POF cases and its synonymies diagnosed from 1950 to 2004 at the Oral Pathology Service of the Federal University of Minas Gerais. The cases were reviewed in hematoxylin-eosin stain and the histological features were evaluated in accordance with the classification WHO. Patient's data about gender, age and race and the lesion's clinical data were obtained from the biopsy request forms, after the definite diagnosis of POF. RESULTS: Seventeen diagnoses of POF were found. Data showed that POF has a higher prevalence in females (88.2%), occurring in the second and fourth decades of life (29.4% each), and in Caucasians (64.7%). The most common location was the posterior region of the mandible (41.1%). It was an asymptomatic lesion (23.5%) with an average size of 1.1 to 2.0 cm (35.2%). The histological findings were: 1) fibroblastic tissue high cellularity (58.8%); 2) scarce odontogenic epithelium (64.7%); 3) inflammation (94.1%) and 4) absence of calcification (58.8%). CONCLUSIONS: Clinical and histological data of POF in Brazilians showed important characteristcs for its diagnosis. This epidemiological data will generate a substantial contribution to the clinical, histological diagnosis and behavior of this lesion.
AIM: The purpose of this study is to present data on a series of peripheral odontogenic fibroma, WHO (World Health Organization)-type (POF), in Brazilians and to compare the results with previously reported studies. METHODS: The study sample was made from the number of POF cases and its synonymies diagnosed from 1950 to 2004 at the Oral Pathology Service of the Federal University of Minas Gerais. The cases were reviewed in hematoxylin-eosin stain and the histological features were evaluated in accordance with the classification WHO. Patient's data about gender, age and race and the lesion's clinical data were obtained from the biopsy request forms, after the definite diagnosis of POF. RESULTS: Seventeen diagnoses of POF were found. Data showed that POF has a higher prevalence in females (88.2%), occurring in the second and fourth decades of life (29.4% each), and in Caucasians (64.7%). The most common location was the posterior region of the mandible (41.1%). It was an asymptomatic lesion (23.5%) with an average size of 1.1 to 2.0 cm (35.2%). The histological findings were: 1) fibroblastic tissue high cellularity (58.8%); 2) scarce odontogenic epithelium (64.7%); 3) inflammation (94.1%) and 4) absence of calcification (58.8%). CONCLUSIONS: Clinical and histological data of POF in Brazilians showed important characteristcs for its diagnosis. This epidemiological data will generate a substantial contribution to the clinical, histological diagnosis and behavior of this lesion.