Literature DB >> 17327263

Finger's "slotted" eye plaque for radiation therapy: treatment of juxtapapillary and circumpapillary intraocular tumours.

Paul T Finger1.   

Abstract

AIM: To create "slotted eye plaques" for the treatment of juxtapapillary and circumpapillary intraocular tumours.
METHODS: Eye plaques were altered such that 8 mm-wide slots (variable length) were created to accommodate the orbital portion of the optic nerve. Thus, as the nerve entered the slot, the plaque's posterior margin extended beyond the optic disc. Radioactive seeds were affixed around the slot, surrounding the juxtapapillary and posterior tumour margins.
RESULTS: As proof of principle, three patients with choroidal melanomas that encircled or were in contact with the optic disc (considered untreatable with a notched eye plaque) were considered to be initial candidates for slotted-plaque radiotherapy. Preoperative three-dimensional C-scan imaging of their optic nerve sheath diameters insured that they would fit in the slotted plaque. Intraoperative ultrasound imaging was used to confirm proper plaque placement. Radiation dosimetry modelling showed that all tumour tissue received a minimum of 85 Gy (despite the gap created by the slot). With relatively short-term follow-up, there has been no evidence of ocular ischaemia, tumour growth or complications attributable to the use of slotted-plaque radiation therapy.
CONCLUSION: Slotted plaques accommodate the retrobulbar optic nerve into the device and thereby shift the treatment zone to improve coverage of both juxtapapillary and circumpapillary intraocular tumours.

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Mesh:

Year:  2007        PMID: 17327263      PMCID: PMC1955638          DOI: 10.1136/bjo.2007.114082

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  19 in total

1.  A 3-dimensional ultrasound C-scan imaging technique for optic nerve measurements.

Authors:  Julian P S Garcia; Patricia T Garcia; Richard B Rosen; Paul T Finger
Journal:  Ophthalmology       Date:  2004-06       Impact factor: 12.079

2.  Proton or stereotactic photon irradiation for posterior uveal melanoma? A planning intercomparison.

Authors:  Stefan Höcht; Roland Stark; Frank Seiler; Jens Heufelder; Nikolaos E Bechrakis; Dino Cordini; Simone Marnitz; Heinz Kluge; Michael H Foerster; Wolfgang Hinkelbein
Journal:  Strahlenther Onkol       Date:  2005-12       Impact factor: 3.621

3.  Long-term results of iodine 125 irradiation of uveal melanoma.

Authors:  S Packer; S Stoller; M L Lesser; F S Mandel; P T Finger
Journal:  Ophthalmology       Date:  1992-05       Impact factor: 12.079

4.  Ultrasound determination of the relationship of radioactive plaques to the base of choroidal melanomas.

Authors:  C J Pavlin; B Japp; E R Simpson; H D McGowan; P J Fitzpatrick
Journal:  Ophthalmology       Date:  1989-04       Impact factor: 12.079

5.  Plaque radiotherapy for juxtapapillary choroidal melanoma. Visual acuity and survival outcome.

Authors:  P De Potter; C L Shields; J A Shields; J R Cater; L W Brady
Journal:  Arch Ophthalmol       Date:  1996-11

6.  Design and dosimetric considerations of a modified COMS plaque: the reusable "seed-guide" insert.

Authors:  Melvin A Astrahan; Andrzej Szechter; Paul T Finger
Journal:  Med Phys       Date:  2005-08       Impact factor: 4.071

7.  Intraoperative echographic localization of iodine 125 episcleral radioactive plaques for posterior uveal melanoma.

Authors:  J W Harbour; T G Murray; S F Byrne; J R Hughes; E K Gendron; F J Ehlies; A M Markoe
Journal:  Retina       Date:  1996       Impact factor: 4.256

8.  Treatment of juxtapapillary melanomas.

Authors:  P K Lommatzsch; R Lommatzsch
Journal:  Br J Ophthalmol       Date:  1991-12       Impact factor: 4.638

9.  Stereotactic radiotherapy in the treatment of juxtapapillary choroidal melanoma: preliminary results.

Authors:  Khaled Emara; Daniel J Weisbrod; Arjun Sahgal; Hugh McGowan; Satish Jaywant; Howard Michaels; David Payne; Melania Pintilie; Normand J Laperriere; E Rand Simpson
Journal:  Int J Radiat Oncol Biol Phys       Date:  2004-05-01       Impact factor: 7.038

10.  Late radiation failures after iodine 125 brachytherapy for uveal melanoma compared with charged-particle (proton or helium ion) therapy.

Authors:  Devron H Char; Stewart Kroll; Theodore L Phillips; Jeanne M Quivey
Journal:  Ophthalmology       Date:  2002-10       Impact factor: 12.079

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  4 in total

1.  Outcomes following Notched Ruthenium-106 Plaque Brachytherapy for Juxtapapillary Choroidal Melanomas.

Authors:  Manvi Manu Sobti; Magdalena Edington; Julie Connolly; David J McLernon; Stefano Schipani; Diana Ritchie; Paul Cauchi; Vikas Chadha
Journal:  Ocul Oncol Pathol       Date:  2021-08-23

2.  Optic disc dose reduction in ocular brachytherapy using 125 I notched COMS plaques: A simulation study based on current clinical practice.

Authors:  Yongsook C Lee; Shih-Chi Lin; Yongbok Kim
Journal:  J Appl Clin Med Phys       Date:  2020-07-12       Impact factor: 2.102

3.  A practical approach to estimating optic disc dose and macula dose without treatment planning in ocular brachytherapy using 125I COMS plaques.

Authors:  Yongsook C Lee; Shih-Chi Lin; Yongbok Kim
Journal:  Radiat Oncol       Date:  2018-11-13       Impact factor: 3.481

4.  Keeping an eye on the ring: COMS plaque loading optimization for improved dose conformity and homogeneity.

Authors:  Nolan L Gagne; Daniel R Cutright; Mark J Rivard
Journal:  J Contemp Brachytherapy       Date:  2012-09-29
  4 in total

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