Literature DB >> 173263

Inhibition of Newcastle disease virus-induced fever in rabbits by cycloheximide.

R Siegert, W K Philipp-Dormston, K Radsak, H Menzel.   

Abstract

Pretreatment with cycloheximide prevents virus-induced fever in rabbits. Compared to the febrile control animals, CH-pretreated afebrile animals exhibit similar concentrations of endogenous pyrogen in the blood and of prostaglandins of the E-group and adenosine 3', 5'-cycle monophosphate in the cerebrospinal fluid. The fever response seems to involve one or several additional so far unknown mediators which are sensitive to cycloheximide.

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Year:  1975        PMID: 173263     DOI: 10.1007/bf01317435

Source DB:  PubMed          Journal:  Arch Virol        ISSN: 0304-8608            Impact factor:   2.574


  19 in total

1.  THE PYROGENS OF MYXOVIRUSES. II. RESISTANCE OF INFLUENZA A PYROGENS TO HEAT, ULTRAVIOLET, AND CHEMICAL TREATMENT.

Authors:  R SIEGERT; P BRAUNE
Journal:  Virology       Date:  1964-10       Impact factor: 3.616

2.  Pyrogenicity of influenza virus in rabbits.

Authors:  I L BENNETT; R R WAGNER; V S LeQUIRE
Journal:  Proc Soc Exp Biol Med       Date:  1949-05

3.  Regulation of adenosine 3',5'-cyclic monophosphate metabolism in cultured neuroblastoma cells.

Authors:  A G Gilman; M Nirenberg
Journal:  Nature       Date:  1971-12-10       Impact factor: 49.962

4.  The prevention by inhibitors of brain proptein synthesis of the hyperactivity and hyperpyrexia produced in rats by monoamine oxidase inhibition and the administration of L-tryptophan or 5-methoxy-N,N-dimethyltryptamine.

Authors:  D G Grahame-Smith
Journal:  J Neurochem       Date:  1972-10       Impact factor: 5.372

5.  [Virus-induced fever and its role in infection defence].

Authors:  R Siegert
Journal:  Verh Dtsch Ges Inn Med       Date:  1973

6.  Studies on the pathogenesis of fever. XIX. Localization of pyrogen in granulocytes.

Authors:  H H Hahn; S F Cheuk; S Elfenbein; W B Wood
Journal:  J Exp Med       Date:  1970-04-01       Impact factor: 14.307

7.  ENDOGENOUS PYROGEN RELEASE FROM RABBIT BLOOD CELLS INCUBATED IN VITRO WITH PARAINFLUENZA VIRUS.

Authors:  E ATKINS; M CRONIN; P ISACSON
Journal:  Science       Date:  1964-12-11       Impact factor: 47.728

8.  Pyrogen fever and prostaglandin-like activity in cerebrospinal fluid.

Authors:  W Feldberg; K P Gupta
Journal:  J Physiol       Date:  1973-01       Impact factor: 5.182

9.  The production of fever by influenzal viruses; factors influencing the febrile response to single injections of virus.

Authors:  R R WAGNER; I L BENNETT; V S LeQUIRE
Journal:  J Exp Med       Date:  1949-10       Impact factor: 14.307

10.  Studies on the pathogenesis of fever with influenzal viruses. I. The appearance of an endogenous pyrogen in the blood following intravenous injection of virus.

Authors:  E ATKINS; W C HUANG
Journal:  J Exp Med       Date:  1958-03-01       Impact factor: 14.307

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  3 in total

1.  Inhibitors of protein and RNA synthesis cause a rapid block in prostaglandin production at the prostaglandin synthase step.

Authors:  J M Fagan; A L Goldberg
Journal:  Proc Natl Acad Sci U S A       Date:  1986-04       Impact factor: 11.205

2.  Group A streptococcal pyrogenic exotoxin: pyrogenicity, alteration of blood-brain barrier, and separation of sites for pyrogenicity and enhancement of lethal endotoxin shock.

Authors:  P M Schlievert; D W Watson
Journal:  Infect Immun       Date:  1978-09       Impact factor: 3.441

3.  Mechanism of fever induction in rabbits.

Authors:  R Siegert; W K Philipp-Dormston; K Radsak; H Menzel
Journal:  Infect Immun       Date:  1976-11       Impact factor: 3.441

  3 in total

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