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Literature DB >> 17325786

Synthetic metallomolecules as agents for the control of DNA structure.

Abstract

This tutorial review summarises B-DNA structure and metallomolecule binding modes and illustrates some DNA structures induced by molecules containing metallic cations. The effects of aquated metal ions, cobalt amines, ruthenium octahedral metal complexes, metallohelicates and platinum complexes such as cis-platin are discussed alongside the techniques of NMR, X-ray crystallography, gel electrophoresis, circular dichroism, linear dichroism and molecular dynamics. The review will be of interest to people interested in both DNA structure and roles of metallomolecules in biological systems.

Entities: Chemical Disease Species

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Year: 2006 PMID： 17325786 DOI： 10.1039/b609495c

Source DB: PubMed Journal: Chem Soc Rev ISSN： 0306-0012 Impact factor: 54.564

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Cited

14 in total

1. Metallo-helical complexes: Resolutely pure helices.

Authors: Janice R Aldrich-Wright
Journal: Nat Chem Date: 2011-12-15 Impact factor: 24.427

2. Theoretical investigation on ruthenium tetraazaporphyrin as potential nitric oxide carrier in biological systems.

Authors: José M M Lima; Valter H C Silva; Lilian T F M Camargo; Heibbe C B de Oliveira; Ademir J Camargo
Journal: J Mol Model Date: 2013-01-08 Impact factor: 1.810

3. Rhodium(III) and iridium(III) complexes with 1,2-naphthoquinone-1-oximate as a bidentate ligand: synthesis, structure, and biological activity.

Authors: Stefan Wirth; Christoph J Rohbogner; Marcin Cieslak; Julia Kazmierczak-Baranska; Stefan Donevski; Barbara Nawrot; Ingo-Peter Lorenz
Journal: J Biol Inorg Chem Date: 2009-12-19 Impact factor: 3.358

Review 4. Structure-based DNA-targeting strategies with small molecule ligands for drug discovery.

Authors: Jia Sheng; Jianhua Gan; Zhen Huang
Journal: Med Res Rev Date: 2013-04-30 Impact factor: 12.944

5. Di- and polynuclear silver(I) saccharinate complexes of tertiary diphosphane ligands: synthesis, structures, in vitro DNA binding, and antibacterial and anticancer properties.

Authors: Veysel T Yilmaz; Elif Gocmen; Ceyda Icsel; Murat Cengiz; Sunde Y Susluer; Orhan Buyukgungor
Journal: J Biol Inorg Chem Date: 2013-10-17 Impact factor: 3.358

10. Luminescent platinum(II) complexes with functionalized N-heterocyclic carbene or diphosphine selectively probe mismatched and abasic DNA.

Authors: Sin Ki Fung; Taotao Zou; Bei Cao; Tianfeng Chen; Wai-Pong To; Chen Yang; Chun-Nam Lok; Chi-Ming Che
Journal: Nat Commun Date: 2016-02-17 Impact factor: 14.919

Synthetic metallomolecules as agents for the control of DNA structure.

1. Metallo-helical complexes: Resolutely pure helices.

2. Theoretical investigation on ruthenium tetraazaporphyrin as potential nitric oxide carrier in biological systems.

3. Rhodium(III) and iridium(III) complexes with 1,2-naphthoquinone-1-oximate as a bidentate ligand: synthesis, structure, and biological activity.

Review 4. Structure-based DNA-targeting strategies with small molecule ligands for drug discovery.

5. Di- and polynuclear silver(I) saccharinate complexes of tertiary diphosphane ligands: synthesis, structures, in vitro DNA binding, and antibacterial and anticancer properties.

6. Bipyrimidine ruthenium(II) arene complexes: structure, reactivity and cytotoxicity.

Review 7. Recent Advances in Developing Small Molecules Targeting Nucleic Acid.

8. In Vitro and in vivo Evaluation of Electrochemotherapy with trans-platinum Analogue trans-[PtCl₂(3-Hmpy)₂].

9. Controlled release of an anti-cancer drug from DNA structured nano-films.

10. Luminescent platinum(II) complexes with functionalized N-heterocyclic carbene or diphosphine selectively probe mismatched and abasic DNA.