Literature DB >> 1732529

Synthesis, stability, and biological evaluation of water-soluble prodrugs of a new echinocandin lipopeptide. Discovery of a potential clinical agent for the treatment of systemic candidiasis and Pneumocystis carinii pneumonia (PCP).

J M Balkovec1, R M Black, M L Hammond, J V Heck, R A Zambias, G Abruzzo, K Bartizal, H Kropp, C Trainor, R E Schwartz.   

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Year:  1992        PMID： 1732529     DOI： 10.1021/jm00079a027

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  14 in total

Review 1.  Treatment of infection due to Pneumocystis carinii.

Authors:  J A Fishman
Journal:  Antimicrob Agents Chemother       Date:  1998-06       Impact factor: 5.191

Review 2.  Antifungal peptides: novel therapeutic compounds against emerging pathogens.

Authors:  A J De Lucca; T J Walsh
Journal:  Antimicrob Agents Chemother       Date:  1999-01       Impact factor: 5.191

Review 3.  Prevention of infection due to Pneumocystis carinii.

Authors:  J A Fishman
Journal:  Antimicrob Agents Chemother       Date:  1998-05       Impact factor: 5.191

4.  Identification of the FKS1 gene of Candida albicans as the essential target of 1,3-beta-D-glucan synthase inhibitors.

Authors:  C M Douglas; J A D'Ippolito; G J Shei; M Meinz; J Onishi; J A Marrinan; W Li; G K Abruzzo; A Flattery; K Bartizal; A Mitchell; M B Kurtz
Journal:  Antimicrob Agents Chemother       Date:  1997-11       Impact factor: 5.191

5.  Preliminary animal pharmacokinetics of the parenteral antifungal agent MK-0991 (L-743,872).

Authors:  R Hajdu; R Thompson; J G Sundelof; B A Pelak; F A Bouffard; J F Dropinski; H Kropp
Journal:  Antimicrob Agents Chemother       Date:  1997-11       Impact factor: 5.191

Review 6.  Compounds active against cell walls of medically important fungi.

Authors:  R F Hector
Journal:  Clin Microbiol Rev       Date:  1993-01       Impact factor: 26.132

7.  Prophylactic effect of FK463, a novel antifungal lipopeptide, against Pneumocystis carinii infection in mice.

Authors:  M Ito; R Nozu; T Kuramochi; N Eguchi; S Suzuki; K Hioki; T Itoh; F Ikeda
Journal:  Antimicrob Agents Chemother       Date:  2000-09       Impact factor: 5.191

8.  Increased antifungal activity of L-733,560, a water-soluble, semisynthetic pneumocandin, is due to enhanced inhibition of cell wall synthesis.

Authors:  M B Kurtz; C Douglas; J Marrinan; K Nollstadt; J Onishi; S Dreikorn; J Milligan; S Mandala; J Thompson; J M Balkovec
Journal:  Antimicrob Agents Chemother       Date:  1994-12       Impact factor: 5.191

9.  Aerosolized L-693,989 for Pneumocystis carinii prophylaxis in rats.

Authors:  M A Powles; D C McFadden; P A Liberator; J W Anderson; E B Vadas; D Meisner; D M Schmatz
Journal:  Antimicrob Agents Chemother       Date:  1994-06       Impact factor: 5.191

10.  New semisynthetic pneumocandins with improved efficacies against Pneumocystis carinii in the rat.

Authors:  D M Schmatz; M A Powles; D McFadden; K Nollstadt; F A Bouffard; J F Dropinski; P Liberator; J Andersen
Journal:  Antimicrob Agents Chemother       Date:  1995-06       Impact factor: 5.191
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