| Literature DB >> 17324605 |
María Rosa Bono1, Raúl Elgueta, Daniela Sauma, Karina Pino, Fabiola Osorio, Paula Michea, Alberto Fierro, Mario Rosemblatt.
Abstract
Knowledge of lymphocyte migration has become a major issue in our understanding of acquired immunity. The selective migration of naïve, effector, memory and regulatory T-cells is a multiple step process regulated by a specific arrangement of cytokines, chemokines and adhesion receptors that guide these cells to specific locations. Recent research has outlined two major pathways of lymphocyte trafficking under homeostatic and inflammatory conditions, one concerning tropism to cutaneous tissue and a second one related to mucosal-associated sites. In this article we will outline our present understanding of the role of cytokines and chemokines as regulators of lymphocyte migration through tissues.Mesh：
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Year: 2007 PMID： 17324605 DOI： 10.1016/j.cytogfr.2007.01.004
Source DB: PubMed Journal: Cytokine Growth Factor Rev ISSN： 1359-6101 Impact factor: 7.638