| Literature DB >> 17323647 |
Nahyun Kim1, Jin Chul Shin, Woncheol Kim, Bang Yeon Hwang, Beom Seok Kim, Young-Soo Hong, Dongho Lee.
Abstract
Two new 6-alkylsalicylic acids, salaceyins A and B were isolated by bioassay-guided fractionation from the culture of the endophytic Streptomyces laceyi MS53 and their structures were determined on the basis of spectroscopic data. Salaceyins A and B exhibited modest cytotoxicity against a human breast cancer cell line (SKBR3) with IC50 values of 3.0 and 5.5 microg/ml, respectively.Entities:
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Year: 2006 PMID: 17323647 DOI: 10.1038/ja.2006.105
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN: 0021-8820 Impact factor: 2.649