Literature DB >> 17323584

Successful treatment of mandibular squamous cell carcinoma in a Malayan sun bear (Helarctos malayanus).

Natalie D Mylniczenko1, Ann L Manharth, Leigh Ann Clayton, Rhonda Feinmehl, Mitch Robbins.   

Abstract

An adult, female Malayan sun bear (Helarctos malayanus) was diagnosed with squamous cell carcinoma of the rostral mandible. Initial treatment included bilateral mandibulectomy rostral to the lingual frenulum followed by intra- and perilesional cisplatin injections. Recovery after the procedure was uneventful and the Malayan sun bear adapted well to a shortened mandible. Histopathology indicated incomplete surgical excision of the tumor; therefore, radiation therapy was instituted weekly for four treatments at 2 Gy in parallel opposed fields (total 4 Gy each treatment) with one additional cisplatin treatment. Two years after initial presentation, the animal showed no recurrence of neoplasia.

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Year:  2005        PMID: 17323584     DOI: 10.1638/03-118.1

Source DB:  PubMed          Journal:  J Zoo Wildl Med        ISSN: 1042-7260            Impact factor:   0.776


  2 in total

1.  Development of an anti-bear podoplanin monoclonal antibody PMab-247 for immunohistochemical analysis.

Authors:  Yoshikazu Furusawa; Junko Takei; Yusuke Sayama; Shinji Yamada; Mika K Kaneko; Yukinari Kato
Journal:  Biochem Biophys Rep       Date:  2019-04-28

2.  Epidemiology and pathological progression of erythematous lip lesions in captive sun bears (Helarctos malayanus).

Authors:  Kirsty Officer; Mathieu Pruvot; Paul Horwood; Daniela Denk; Kris Warren; Vibol Hul; Nhim Thy; Nev Broadis; Philippe Dussart; Bethany Jackson
Journal:  PLoS One       Date:  2020-12-01       Impact factor: 3.240

  2 in total

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