Literature DB >> 17322136

Aging gracefully: a retrospective analysis of functional status in Okinawan centenarians.

D Craig Willcox1, Bradley J Willcox, Sanae Shimajiri, Sayuri Kurechi, Makoto Suzuki.   

Abstract

OBJECTIVE: This study retrospectively explored the late-life functional status of Okinawan centenarians.
METHODS: Activities of daily living were measured retrospectively at five time points (10, 5, 3, and 1 year prior and present) for 22 centenarians in relation to seven physical, two sensory, and two cognitive functions using the Inoue Index.
RESULTS: In all, 82% of individuals were still functioning independently at a mean age of 92 years and almost two-thirds were still functioning independently at a mean age of 97 years.
CONCLUSION: Preliminary analyses suggest high functional status in Okinawan centenarians throughout their 90 s. The genetic and environmental factors contributing to this successful aging phenomenon deserve further investigation.

Mesh:

Year:  2007        PMID: 17322136     DOI: 10.1097/JGP.0b013e31803190cc

Source DB:  PubMed          Journal:  Am J Geriatr Psychiatry        ISSN: 1064-7481            Impact factor:   4.105


  12 in total

1.  Predicting survival and morbidity-free survival to very old age.

Authors:  Rachel S Newson; Jacqueline C M Witteman; Oscar H Franco; Bruno H C Stricker; Monique M B Breteler; Albert Hofman; Henning Tiemeier
Journal:  Age (Dordr)       Date:  2010-06-01

2.  Successful aging: definitions and prediction of longevity and conversion to mild cognitive impairment.

Authors:  Selam Negash; Glenn E Smith; Shane Pankratz; Jeremiah Aakre; Yonas E Geda; Rosebud O Roberts; David S Knopman; Bradley F Boeve; Robert J Ivnik; Ronald C Petersen
Journal:  Am J Geriatr Psychiatry       Date:  2011-06       Impact factor: 4.105

3.  Becoming centenarians: disease and functioning trajectories of older US Adults as they survive to 100.

Authors:  Jennifer A Ailshire; Hiram Beltrán-Sánchez; Eileen M Crimmins
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2014-08-18       Impact factor: 6.053

4.  Genetic analysis of TOR complex gene variation with human longevity: a nested case-control study of American men of Japanese ancestry.

Authors:  Brian J Morris; Timothy A Donlon; Qimei He; John S Grove; Kamal H Masaki; Ayako Elliott; D Craig Willcox; Richard Allsopp; Bradley J Willcox
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2014-03-03       Impact factor: 6.053

5.  Centenarians--a useful model for healthy aging? A 29-year follow-up of hospitalizations among 40,000 Danes born in 1905.

Authors:  Henriette Engberg; Anna Oksuzyan; Bernard Jeune; James W Vaupel; Kaare Christensen
Journal:  Aging Cell       Date:  2009-03-27       Impact factor: 9.304

6.  FOXO3A genotype is strongly associated with human longevity.

Authors:  Bradley J Willcox; Timothy A Donlon; Qimei He; Randi Chen; John S Grove; Katsuhiko Yano; Kamal H Masaki; D Craig Willcox; Beatriz Rodriguez; J David Curb
Journal:  Proc Natl Acad Sci U S A       Date:  2008-09-02       Impact factor: 11.205

7.  Secrets of healthy aging and longevity from exceptional survivors around the globe: lessons from octogenarians to supercentenarians.

Authors:  Bradley J Willcox; D Craig Willcox; Luigi Ferrucci
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2008-11       Impact factor: 6.053

8.  Modern Medicine: Towards Prevention, Cure, Well-being and Longevity.

Authors:  Ajai R Singh
Journal:  Mens Sana Monogr       Date:  2010-01

9.  Centenarians Today: New Insights on Selection from the 5-COOP Study.

Authors:  Jean-Marie Robine; Siu Lan Karen Cheung; Yasuhiko Saito; Bernard Jeune; Marti G Parker; François R Herrmann
Journal:  Curr Gerontol Geriatr Res       Date:  2011-03-07

10.  Centenarian studies: important contributors to our understanding of the aging process and longevity.

Authors:  Donald Craig Willcox; Bradley J Willcox; Leonard W Poon
Journal:  Curr Gerontol Geriatr Res       Date:  2011-07-13
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