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Literature DB >> 17320513

Noncoding RNAs and intranuclear positioning in monoallelic gene expression.

Abstract

Mammalian X inactivation, imprinting, and allelic exclusion are classic examples of monoallelic gene expression. Two emerging themes are thought to be critical for monoallelic expression: (1) noncoding, often antisense, transcription linked to differential chromatin marks on otherwise homologous alleles and (2) physical segregation of alleles to separate domains within the nucleus. Here, we highlight recent progress in identifying these phenomena as possible key regulatory mechanisms of monoallelic expression.

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Year: 2007 PMID： 17320513 DOI： 10.1016/j.cell.2007.01.032

Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582

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Cited

44 in total

1. A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression.

Authors: Delphine Bernard; Kannanganattu V Prasanth; Vidisha Tripathi; Sabrina Colasse; Tetsuya Nakamura; Zhenyu Xuan; Michael Q Zhang; Frédéric Sedel; Laurent Jourdren; Fanny Coulpier; Antoine Triller; David L Spector; Alain Bessis
Journal: EMBO J Date: 2010-08-20 Impact factor: 11.598

2. Two distinct mechanisms of silencing by the KvDMR1 imprinting control region.

Authors: Jong-Yeon Shin; Galina V Fitzpatrick; Michael J Higgins
Journal: EMBO J Date: 2007-12-13 Impact factor: 11.598

3. Spatial allelic imbalance of BCL2 genes and chromosome 18 territories in nonneoplastic and neoplastic cervical squamous epithelium.

Authors: Thorsten Wiech; Stefan Stein; Victoria Lachenmaier; Eberhard Schmitt; Jutta Schwarz-Finsterle; Elisabeth Wiech; Georg Hildenbrand; Martin Werner; Michael Hausmann
Journal: Eur Biophys J Date: 2009-06-03 Impact factor: 1.733

4. Chromatin associated sense and antisense noncoding RNAs are transcribed from the var gene family of virulence genes of the malaria parasite Plasmodium falciparum.

Authors: Christian Epp; Felomena Li; Cali A Howitt; Thanat Chookajorn; Kirk W Deitsch
Journal: RNA Date: 2008-11-26 Impact factor: 4.942

Noncoding RNAs and intranuclear positioning in monoallelic gene expression.

1. A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression.

2. Two distinct mechanisms of silencing by the KvDMR1 imprinting control region.

3. Spatial allelic imbalance of BCL2 genes and chromosome 18 territories in nonneoplastic and neoplastic cervical squamous epithelium.

4. Chromatin associated sense and antisense noncoding RNAs are transcribed from the var gene family of virulence genes of the malaria parasite Plasmodium falciparum.

5. May anomalous X chromosome methylation be responsible for the spontaneous abortion of a male foetus?

Review 6. Epigenetic principles and mechanisms underlying nervous system functions in health and disease.

7. Histone acetylation and its role in embryonic stem cell differentiation.

8. Allele-specific nuclear positioning of the monoallelically expressed astrocyte marker GFAP.

9. Strand selective generation of endo-siRNAs from the Na/phosphate transporter gene Slc34a1 in murine tissues.

10. Aberrant allele-specific replication, independent of parental origin, in blood cells of cancer patients.