Literature DB >> 17320386

Synthesis and antifungal activity of 6-arylamino-phthalazine-5,8-diones and 6,7-bis(arylthio)-phthalazine-5,8-diones.

Chung-Kyu Ryu1, Rae-Eun Park, Mi-Young Ma, Ji-Hee Nho.   

Abstract

6-Arylamino-phthalazine-5,8-diones and 6,7-bis(arylthio)-phthalazine-5,8-diones were synthesized and tested for in vitro antifungal activity against two pathogenic strains of fungi. Among those tested, many compounds showed good antifungal activity. The results suggest that phthalazine-5,8-diones would be potent antifungal agents.

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Year:  2007        PMID： 17320386     DOI： 10.1016/j.bmcl.2007.02.003

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  8 in total

1.  Magnetically recoverable Fe3O4 nanocatalyst for the synthesis of biodynamically significant 1H-pyrazolo[1,2-b]phthalazine-5,10-diones derivatives and its DFT study.

Authors:  Mohd Danish Ansari; Hozeyfa Sagir; Vijay B Yadav; Neetu Yadav; Ankit Verma; Sonam Shakya; Manjit Singh; I R Siddiqui
Journal:  Mol Divers       Date:  2022-10-07       Impact factor: 3.364

2.  Highly Active Small Aminated Quinolinequinones against Drug-Resistant Staphylococcus aureus and Candida albicans.

Authors:  Hatice Yıldırım; Nilüfer Bayrak; Mahmut Yıldız; Fatıma Nur Yılmaz; Emel Mataracı-Kara; Deepak Shilkar; Venkatesan Jayaprakash; Amaç Fatih TuYuN
Journal:  Molecules       Date:  2022-05-03       Impact factor: 4.927

3.  Palladium-catalyzed bisthiolation of terminal alkynes for the assembly of diverse (Z)-1,2-bis(arylthio)alkene derivatives.

Authors:  Yin-Long Lai; Shaoxi Yan; Dan He; Li-Zhen Zhou; Zi-Shen Chen; Yu-Long Du; Jianxiao Li
Journal:  RSC Adv       Date:  2021-08-23       Impact factor: 4.036

4.  Design, synthesis and biological evaluation of ezrin inhibitors targeting metastatic osteosarcoma.

Authors:  Mikell Paige; George Kosturko; Güllay Bulut; Matthew Miessau; Said Rahim; Jeffrey A Toretsky; Milton L Brown; Aykut Üren
Journal:  Bioorg Med Chem       Date:  2013-11-14       Impact factor: 3.641

5.  4-(4-Methyl-phen-yl)-2-(prop-2-yn-1-yl)phthalazin-1(2H)-one.

Authors:  M K Usha; S Madan Kumar; P C Shyma; B Kalluraya; N K Lokanath; D Revannasiddaiah
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2014-01-15

6.  A new efficient domino approach for the synthesis of pyrazolyl-phthalazine-diones. Antiradical activity of novel phenolic products.

Authors:  Dušica Simijonović; Zorica D Petrović; Vesna M Milovanović; Vladimir P Petrović; Goran A Bogdanović
Journal:  RSC Adv       Date:  2018-05-04       Impact factor: 4.036

7.  Preparation, characterization, and use of novel Cu@Fe3O4 MNPs in the synthesis of tetrahydrobenzimidazo[2,1-b]quinazolin-1(2H)-ones and 2H-indazolo[2,1-b]phthalazine-triones under solvent-free conditions.

Authors:  Lilin Jiang; Zumrat Druzhinin
Journal:  RSC Adv       Date:  2019-05-14       Impact factor: 4.036

8.  Investigating pyridazine and phthalazine exchange in a series of iridium complexes in order to define their role in the catalytic transfer of magnetisation from para-hydrogen.

Authors:  Kate M Appleby; Ryan E Mewis; Alexandra M Olaru; Gary G R Green; Ian J S Fairlamb; Simon B Duckett
Journal:  Chem Sci       Date:  2015-04-28       Impact factor: 9.825
  8 in total

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