Literature DB >> 17318836

Trauma and posttraumatic stress disorder in treatment-resistant obsessive-compulsive disorder.

Beth S Gershuny1, Lee Baer, Holly Parker, Emily L Gentes, Alison L Infield, Michael A Jenike.   

Abstract

Prior research has indicated a seemingly unique relation between obsessive-compulsive disorder (OCD) and posttraumatic stress disorder (PTSD) that appears to relate to negative treatment outcome for OCD. However, to date, the prevalence of trauma and PTSD in individuals seeking treatment for OCD is unclear. To begin to address this gap, this study assessed history of traumatic experiences and current PTSD in individuals seeking treatment for treatment-resistant OCD. Trauma predictors of PTSD severity also were examined in this sample. Participants included 104 individuals diagnosed with treatment-resistant OCD who sought treatment over the course of 1 year from OCD specialty treatment facilities. Data were collected via naturalistic retrospective chart reviews of pre-treatment clinical intake files. Findings revealed that 82% of participants reported a history of trauma. Over 39% of the overall sample met criteria for PTSD, whereas almost 50% of individuals with a trauma history met criteria for PTSD. Interpersonal traumas and greater frequency of traumas were most predictive of PTSD severity, and individuals diagnosed with OCD and additional major depressive disorder (MDD) or borderline personality disorder (BPD) appeared at particular risk for a comorbid PTSD diagnosis. PTSD may be relatively common in individuals diagnosed with treatment-resistant OCD; and interpersonal traumas, MDD, and BPD may play a relatively strong predictive role in PTSD diagnosis and severity in such OCD patients.

Entities:  

Mesh:

Year:  2008        PMID: 17318836     DOI: 10.1002/da.20284

Source DB:  PubMed          Journal:  Depress Anxiety        ISSN: 1091-4269            Impact factor:   6.505


  23 in total

1.  General personality dimensions, impairment and treatment response in obsessive-compulsive disorder.

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2.  Treating a 16 Year Old with a History of Severe Bullying: Supplementing Cognitive Behavioural Therapy with EMDR within the Context of a Case Formulation Approach.

Authors:  Alice Taylor; Niel H McLachlan
Journal:  J Child Adolesc Trauma       Date:  2019-05-06

3.  Specificity of fear and disgust experienced during traumatic interpersonal victimization in predicting posttraumatic stress and contamination-based obsessive-compulsive symptoms.

Authors:  Christal L Badour; Stephanie Bown; Thomas G Adams; Liviu Bunaciu; Matthew T Feldner
Journal:  J Anxiety Disord       Date:  2012-03-14

4.  Traumatic events and obsessive compulsive disorder in children and adolescents: is there a link?

Authors:  Daniel L Lafleur; Carter Petty; Elizabeth Mancuso; Katherine McCarthy; Joseph Biederman; Alyssa Faro; Hannah C Levy; Daniel A Geller
Journal:  J Anxiety Disord       Date:  2010-12-27

5.  Are trauma and dissociation related to treatment resistance in patients with obsessive-compulsive disorder?

Authors:  Umit B Semiz; Leman Inanc; Cigdem H Bezgin
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2013-11-09       Impact factor: 4.328

Review 6.  Anxiety and affective disorder comorbidity related to serotonin and other neurotransmitter systems: obsessive-compulsive disorder as an example of overlapping clinical and genetic heterogeneity.

Authors:  Dennis L Murphy; Pablo R Moya; Meredith A Fox; Liza M Rubenstein; Jens R Wendland; Kiara R Timpano
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2013-02-25       Impact factor: 6.237

7.  The impact of trauma and post-traumatic stress disorder on the treatment response of patients with obsessive-compulsive disorder.

Authors:  Roseli Gedanke Shavitt; Carolina Valério; Victor Fossaluza; Elizabeth Meyer da Silva; Quirino Cordeiro; Juliana Belo Diniz; Cristina Belotto-Silva; Aristides Volpato Cordioli; Jair Mari; Eurípedes Constantino Miguel
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2010-03       Impact factor: 5.270

8.  The impact of lifetime PTSD on the seven-year course and clinical characteristics of OCD.

Authors:  Rachel Ojserkis; Christina L Boisseau; Madhavi K Reddy; Maria C Mancebo; Jane L Eisen; Steven A Rasmussen
Journal:  Psychiatry Res       Date:  2017-09-19       Impact factor: 3.222

Review 9.  Propranolol's effects on the consolidation and reconsolidation of long-term emotional memory in healthy participants: a meta-analysis.

Authors:  Michelle H Lonergan; Lening A Olivera-Figueroa; Roger K Pitman; Alain Brunet
Journal:  J Psychiatry Neurosci       Date:  2013-07       Impact factor: 6.186

10.  Attention Deficit Hyperactivity Disorder, Impulsivity, Anxiety, and Depression Symptoms Mediating the Relationship Between Childhood Trauma and Symptoms Severity of Obsessive-Compulsive Disorder.

Authors:  Adnan Çoban; Oğuz Tan
Journal:  Noro Psikiyatr Ars       Date:  2019-08-16       Impact factor: 1.339

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