Literature DB >> 17317172

Methyl 2-(2-(4-formylphenoxy)acetamido)-2-substituted acetate derivatives: a new class of acetylcholinesterase inhibitors.

Huan Wen1, Yayao Zhou, Chonglan Lin, Hui Ge, Lin Ma, Zihou Wang, Wenlie Peng, Huacan Song.   

Abstract

A new class of inhibitors of acetylcholinesterase (methyl 2-(2-(4-formylphenoxy)acetamido)-2-substituted acetate derivatives) is described. Compounds 4b and 4i were found to be more potent than galanthamine in inhibiting acetylcholinesterase.

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Year:  2007        PMID: 17317172     DOI: 10.1016/j.bmcl.2007.01.091

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

1.  4-Hydroxybenzyl alcohol derivatives and their sedative-hypnotic activities.

Authors:  Hong-Yan Zhu; Di Zhang; Qi Zhang; Yan Zhao; Zhong-Mei He; Yu-Gang Gao; Lian-Xue Zhang
Journal:  RSC Adv       Date:  2018-05-29       Impact factor: 4.036

2.  A novel class of selective acetylcholinesterase inhibitors: synthesis and evaluation of (E)-2-(benzo[d]thiazol-2-yl)-3-heteroarylacrylonitriles.

Authors:  Pedro de la Torre; Luis Astudillo Saavedra; Julio Caballero; Jairo Quiroga; Jans H Alzate-Morales; Margarita Gutiérrez Cabrera; Jorge Trilleras
Journal:  Molecules       Date:  2012-10-15       Impact factor: 4.411

  2 in total

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