| Literature DB >> 17315968 |
Jian Lu Chen1, Michael R Kernan, Shivanand D Jolad, Cheryl A Stoddart, Mark Bogan, Raymond Cooper.
Abstract
Four new compounds, belonging to the tetranortriterpenoid family, named dysoxylins A-D (1-4), isolated from Dysoxylum gaudichaudianum, were found to exhibit potent antiviral activity against respiratory syncytial virus (RSV). These structures were determined by NMR spectroscopy and mass spectrometry and were shown to have anti-RSV EC50 activities in the range 1.0-4.0 microg/mL in cytopathic effect inhibition and plaque reduction assays.Entities:
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Year: 2007 PMID： 17315968 DOI： 10.1021/np060398y
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050