Literature DB >> 17315806

Propylthiouracil (PROP)--a tool to determine taster status in relation to caries experience, streptococcus mutans levels and dietary preferences in children.

Priya Verma1, Vabitha Shetty, Amitha M Hegde.   

Abstract

PURPOSE: Dental caries remains the single most common disease of childhood that is neither self-limiting nor amenable to short term pharmacological management. Hence, there is a need to identify and institute preventive measures for those children who are at a greater risk for developing dental caries to determine the prevalence of tasters and non tasters among the group of school aged children. To compare and contrast the prevalence of dental caries, S. mutans levels and dietary preferences in children with different genetic sensitivity levels to the bitter taste of PROP.
METHOD: A total no of 500 children belonging to the age group of 6-12 years of both sexes were recruited from A.B. Shetty Memorial Institute of Dental Sciences in Mangalore, India. PROP sensitivity test was carried out to determine the inherent genetic ability to taste a bitter or sweet substance. Estimation of Streptococcus mutans levels were done, a questionnaire was given to evaluate their dietary habits and the caries experience was recorded Collected data were tabulated and subjected for statistical analysis using Pearson Chi - square test of significance.
RESULTS: The results suggested that there was increase in the caries experience and S. mutans levels among the group of non tasters as compared to tasters. Tasters tended to be sweet dislikers and non tasters tended to be sweet likers. On the whole tasters had a healthier dentition as compared to non tasters.
CONCLUSION: The PROP test proved to be a useful tool in determining the genetic sensitivity levels of bitter taste. Knowledge of an individuals taste perception can help us in identifying the children who are at higher risk for dental caries.

Entities:  

Mesh:

Substances:

Year:  2006        PMID: 17315806     DOI: 10.17796/jcpd.31.2.34302r2857511268

Source DB:  PubMed          Journal:  J Clin Pediatr Dent        ISSN: 1053-4628            Impact factor:   1.065


  8 in total

1.  Phenylthiocarbamide taste sensitivity is associated with sinonasal symptoms in healthy adults.

Authors:  Douglas R Farquhar; Kevin J Kovatch; James N Palmer; Frances S Shofer; Nithin D Adappa; Noam A Cohen
Journal:  Int Forum Allergy Rhinol       Date:  2014-12-22       Impact factor: 3.858

2.  Genetic sensitivity to bitter taste of 6-n Propylthiouracil: A useful diagnostic aid to detect early childhood caries in pre-school children.

Authors:  Raghavendra Pidamale; B Sowmya; Ann Thomas; Tony Jose
Journal:  Indian J Hum Genet       Date:  2012-01

3.  Caries risk in children of Udaipur City, India using genetic taste sensitivity to 6-n-propylthiouracil.

Authors:  Payel Karmakar; Ruchi Arora; Chhaya Patel; Bhumi Sarvaiya; Aditi Singh; Mittal Patel
Journal:  J Int Soc Prev Community Dent       Date:  2016 Nov-Dec

4.  Digit Ratio and Dental Caries: A Sexually Dimorphic Trait.

Authors:  Priya Verma; Amitha M Hegde
Journal:  Int J Clin Pediatr Dent       Date:  2017-02-01

5.  Evaluating the Mechanical Properties, and Calcium and Fluoride Release of Glass-Ionomer Cement Modified with Chicken Eggshell Powder.

Authors:  Gehan Allam; Ola Abd El-Geleel
Journal:  Dent J (Basel)       Date:  2018-08-18

6.  Correlation of Mother and Child's Taste Perception and their Caries Experience.

Authors:  K Abhiram; A J Sai Sankar; E Sridevi; M Sridhar; K Pranitha; D Aruna
Journal:  Contemp Clin Dent       Date:  2019 Jul-Sep

7.  Association between genetic taste sensitivity, 2D:4D ratio, dental caries prevalence, and salivary flow rate in 6-14-year-old children: a cross-sectional study.

Authors:  Chintamaneni Raja Lakshmi; Doppalapudi Radhika; Mpv Prabhat; Sujana Mulk Bhavana; Nallamilli Sai Madhavi
Journal:  J Dent Res Dent Clin Dent Prospects       Date:  2016-08-17

8.  Clinical and Radiographic Success of Three Adhesive Restorative Materials in Primary Molar Proximal Lesions: A Randomized Clinical Trial.

Authors:  S K Inthihas; S V S G Nirmala; Venkata Ratnakumar Rudhravarm
Journal:  Contemp Clin Dent       Date:  2019 Jul-Sep
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.