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Literature DB >> 17314970

Melanocyte biology and skin pigmentation.

Abstract

Melanocytes are phenotypically prominent but histologically inconspicuous skin cells. They are responsible for the pigmentation of skin and hair, and thereby contribute to the appearance of skin and provide protection from damage by ultraviolet radiation. Pigmentation mutants in various species are highly informative about basic genetic and developmental pathways, and provide important clues to the processes of photoprotection, cancer predisposition and even human evolution. Skin is the most common site of cancer in humans. Continued understanding of melanocyte contributions to skin biology will hopefully provide new opportunities for the prevention and treatment of skin diseases.

Entities: Disease Species

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Year: 2007 PMID： 17314970 DOI： 10.1038/nature05660

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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Cited

325 in total

1. Gene expression analysis identifies new candidate genes associated with the development of black skin spots in Corriedale sheep.

Authors: Francisco Peñagaricano; Pilar Zorrilla; Hugo Naya; Carlos Robello; Jorge I Urioste
Journal: J Appl Genet Date: 2011-09-28 Impact factor: 3.240

2. mHealth spectroscopy of blood hemoglobin with spectral super-resolution.

Authors: Sang Mok Park; Michelle A Visbal-Onufrak; Md Munirul Haque; Martin C Were; Violet Naanyu; Md Kamrul Hasan; Young L Kim
Journal: Optica Date: 2020-06-20 Impact factor: 11.104

Review 3. Current position of TNF-α in melanomagenesis.

Authors: Iuliana Nenu; Diana Tudor; Adriana Gabriela Filip; Ioana Baldea
Journal: Tumour Biol Date: 2015-08-18

4. STIM1 activation of adenylyl cyclase 6 connects Ca²⁺ and cAMP signaling during melanogenesis.

Authors: Rajender K Motiani; Jyoti Tanwar; Desingu Ayyappa Raja; Ayushi Vashisht; Shivangi Khanna; Sachin Sharma; Sonali Srivastava; Sridhar Sivasubbu; Vivek T Natarajan; Rajesh S Gokhale
Journal: EMBO J Date: 2018-01-08 Impact factor: 11.598

5. Morph-specific genetic and environmental variation in innate and acquired immune response in a color polymorphic raptor.

Authors: Laura Gangoso; Alexandre Roulin; Anne-Lyse Ducrest; Juan Manuel Grande; Jordi Figuerola
Journal: Oecologia Date: 2015-04-04 Impact factor: 3.225

6. Microarray analysis sheds light on the dedifferentiating role of agouti signal protein in murine melanocytes via the Mc1r.

Authors: Elodie Le Pape; Thierry Passeron; Alessio Giubellino; Julio C Valencia; Rainer Wolber; Vincent J Hearing
Journal: Proc Natl Acad Sci U S A Date: 2009-01-27 Impact factor: 11.205

Melanocyte biology and skin pigmentation.

1. Gene expression analysis identifies new candidate genes associated with the development of black skin spots in Corriedale sheep.

2. mHealth spectroscopy of blood hemoglobin with spectral super-resolution.

Review 3. Current position of TNF-α in melanomagenesis.

4. STIM1 activation of adenylyl cyclase 6 connects Ca²⁺ and cAMP signaling during melanogenesis.

5. Morph-specific genetic and environmental variation in innate and acquired immune response in a color polymorphic raptor.

6. Microarray analysis sheds light on the dedifferentiating role of agouti signal protein in murine melanocytes via the Mc1r.

Review 7. MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentation.

8. A functional SNP in the MDM2 promoter, pigmentary phenotypes, and risk of skin cancer.

Review 9. Topical treatment strategies to manipulate human skin pigmentation.

Review 10. Physiological factors that regulate skin pigmentation.

Melanocyte biology and skin pigmentation.

1. Gene expression analysis identifies new candidate genes associated with the development of black skin spots in Corriedale sheep.

2. mHealth spectroscopy of blood hemoglobin with spectral super-resolution.

Review 3. Current position of TNF-α in melanomagenesis.

4. STIM1 activation of adenylyl cyclase 6 connects Ca2+ and cAMP signaling during melanogenesis.

5. Morph-specific genetic and environmental variation in innate and acquired immune response in a color polymorphic raptor.

6. Microarray analysis sheds light on the dedifferentiating role of agouti signal protein in murine melanocytes via the Mc1r.

Review 7. MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentation.

8. A functional SNP in the MDM2 promoter, pigmentary phenotypes, and risk of skin cancer.

Review 9. Topical treatment strategies to manipulate human skin pigmentation.

Review 10. Physiological factors that regulate skin pigmentation.

4. STIM1 activation of adenylyl cyclase 6 connects Ca²⁺ and cAMP signaling during melanogenesis.