Literature DB >> 17313125

Time is brain!

A Ross Naylor1.   

Abstract

Carotid endarterectomy (CEA) is a proven treatment in the prevention of stroke, but its overall effectiveness is reduced by excessive delays from symptom to surgery. Specifically, delaying surgery in symptomatic patients with 50-99% NASCET stenoses (70-99% ECST) for >12 weeks prevents only eight strokes per 1000 CEAs in the long term. This is a very depressing observation as the 2004 Sentinel Audit observed that only 50% of stroke patients in the UK will have undergone a Duplex scan by 12 weeks. Excessive delays prior to surgery not only undermine professional confidence in the role of CEA, but they effectively mean that while every patient is exposed to the risks of surgery, many may gain little in the way of long-term stroke prevention. Many of the issues debated in this review will only be resolved by a paradigm shift in political emphasis, but surgeons too have a responsibility to recognise and correct important deficiencies within their own practice.

Entities:  

Mesh:

Year:  2007        PMID: 17313125     DOI: 10.1016/s1479-666x(07)80108-9

Source DB:  PubMed          Journal:  Surgeon        ISSN: 1479-666X            Impact factor:   2.392


  9 in total

1.  Dual antiplatelet therapy for acute minor ischemic stroke or transient ischemic attack.

Authors:  Stavros K Kakkos; John Ellul; Ioannis Ntouvas; Spyros I Papadoulas
Journal:  Ann Transl Med       Date:  2015-08

2.  RACE to protect brains.

Authors:  Thomas E Rix; Inderjit Singh; Robert Insall; Jawaharlal Senaratne
Journal:  Ann R Coll Surg Engl       Date:  2010-07-07       Impact factor: 1.891

Review 3.  Temporal trends in safety of carotid endarterectomy in asymptomatic patients: systematic review.

Authors:  Alex B Munster; Angelo J Franchini; Mahim I Qureshi; Ankur Thapar; Alun H Davies
Journal:  Neurology       Date:  2015-06-26       Impact factor: 9.910

4.  Improving the provision of carotid endarterectomy in line with UK Government targets requires more than just motivated surgeons.

Authors:  Claire Brown; A Ross Naylor
Journal:  Ann R Coll Surg Engl       Date:  2009-04-02       Impact factor: 1.891

5.  The National Stroke Strategy - is it achievable?

Authors:  T D Reid; L J Finney; A R Hedges
Journal:  Ann R Coll Surg Engl       Date:  2009-08-14       Impact factor: 1.891

Review 6.  The current management of carotid atherosclerotic disease: who, when and how?

Authors:  Jens C Ritter; Mark R Tyrrell
Journal:  Interact Cardiovasc Thorac Surg       Date:  2012-11-29

Review 7.  Comparative efficacy of different acute reperfusion therapies for acute ischemic stroke: a comprehensive benefit-risk analysis of clinical trials.

Authors:  Georgios Tsivgoulis; John Alleman; Aristeidis H Katsanos; Andrew D Barreto; Martin Kohrmann; Peter D Schellinger; Carlos A Molina; Andrei V Alexandrov
Journal:  Brain Behav       Date:  2014-09-11       Impact factor: 2.708

Review 8.  Update on the evaluation of transient vision loss.

Authors:  John H Pula; Katherine Kwan; Carlen A Yuen; Jorge C Kattah
Journal:  Clin Ophthalmol       Date:  2016-02-11

Review 9.  Timing of carotid endarterectomy and clinical outcomes.

Authors:  Bilal Azhar; Arsalan Wafi; James Budge; Ian Loftus
Journal:  Ann Transl Med       Date:  2020-10
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.