| Literature DB >> 17311391 |
J Stephen Clark1, Damian M Grainger, Alexandra A-C Ehkirch, Alexander J Blake, Claire Wilson.
Abstract
The tetracyclic fused polyether core of the marine natural product hemibrevetoxin B has been prepared in an efficient manner by using a strategy in which ring-closing metathesis (RCM) reactions were employed for ring synthesis. Simultaneous construction of the A and D rings was accomplished by double two-directional RCM of a tetraene. [reaction: see text]Entities:
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Year: 2007 PMID： 17311391 DOI： 10.1021/ol0630651
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005