Literature DB >> 17311250

Proposals for standardized protocols for cytogenetic analyses of acute leukemias, chronic lymphocytic leukemia, chronic myeloid leukemia, chronic myeloproliferative disorders, and myelodysplastic syndromes.

Claudia Haferlach1, Harald Rieder, Debra M Lillington, Nicole Dastugue, Anne Hagemeijer, Jochen Harbott, Stephan Stilgenbauer, Sakari Knuutila, Bertil Johansson, Christa Fonatsch.   

Abstract

The impact of cytogenetic characterization based on chromosome banding analyses and fluorescence in situ hybridization on clinical decision making has increased dramatically during recent years. Therefore, laboratory techniques have to be optimized to provide reliable results for optimal patient care. In addition, quick and correct results save time and money by preventing unnecessary additional diagnostics and suboptimal treatment approaches. It was our aim to present proposals for standardized protocols to improve the diagnosis, and hence the treatment outcome, of hematologic malignancies. (c) 2007 Wiley-Liss, Inc.

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Year:  2007        PMID： 17311250     DOI： 10.1002/gcc.20433

Source DB:  PubMed          Journal:  Genes Chromosomes Cancer        ISSN： 1045-2257            Impact factor:   5.006


  19 in total

1.  Array-based comparative genomic hybridization detects copy number variations with prognostic relevance in 80% of ALL with normal karyotype or failed chromosome analysis.

Authors:  V Mühlbacher; T Haferlach; W Kern; M Zenger; S Schnittger; C Haferlach
Journal:  Leukemia       Date:  2015-10-09       Impact factor: 11.528

2.  Customized oligonucleotide array-based comparative genomic hybridization as a clinical assay for genomic profiling of chronic lymphocytic leukemia.

Authors:  Rachel Sargent; Dan Jones; Lynne V Abruzzo; Hui Yao; Jaime Bonderover; Marissa Cisneros; William G Wierda; Michael J Keating; Rajyalakshmi Luthra
Journal:  J Mol Diagn       Date:  2008-12-12       Impact factor: 5.568

3.  The European LeukemiaNet: achievements and perspectives.

Authors:  Rüdiger Hehlmann; David Grimwade; Bengt Simonsson; Jane Apperley; Michele Baccarani; Tiziano Barbui; Giovanni Barosi; Renato Bassan; Marie C Béné; Ute Berger; Thomas Büchner; Alan Burnett; Nicolas C P Cross; Theo J M de Witte; Hartmut Döhner; Hervé Dombret; Hermann Einsele; Georg Engelich; Robin Foà; Christa Fonatsch; Nicola Gökbuget; Elaine Gluckman; Alois Gratwohl; Francois Guilhot; Claudia Haferlach; Thorsten Haferlach; Michael Hallek; Jörg Hasford; Andreas Hochhaus; Dieter Hoelzer; Jean-Jaques Kiladjian; Boris Labar; Per Ljungman; Ulrich Mansmann; Dietger Niederwieser; Gert Ossenkoppele; José M Ribera; Harald Rieder; Hubert Serve; Petra Schrotz-King; Miguel A Sanz; Susanne Saussele
Journal:  Haematologica       Date:  2010-11-03       Impact factor: 9.941

4.  High number of additional genetic lesions in acute myeloid leukemia with t(8;21)/RUNX1-RUNX1T1: frequency and impact on clinical outcome.

Authors:  M-T Krauth; C Eder; T Alpermann; U Bacher; N Nadarajah; W Kern; C Haferlach; T Haferlach; S Schnittger
Journal:  Leukemia       Date:  2014-01-09       Impact factor: 11.528

5.  WT1 mutations are secondary events in AML, show varying frequencies and impact on prognosis between genetic subgroups.

Authors:  M-T Krauth; T Alpermann; U Bacher; C Eder; F Dicker; M Ulke; S Kuznia; N Nadarajah; W Kern; C Haferlach; T Haferlach; S Schnittger
Journal:  Leukemia       Date:  2014-08-11       Impact factor: 11.528

6.  Fixed nuclei as alternative template of BIOMED-2 multiplex polymerase chain reaction for immunoglobulin gene clonality testing in B-cell malignancies.

Authors:  Yuan Tang; Jie Chen; Jianchao Wang; Ke Zheng; Dianying Liao; Xiaomei Liao; Weiping Liu; Lin Wang
Journal:  Am J Blood Res       Date:  2015-12-25

7.  Cytogenetic follow-up by karyotyping and fluorescence in situ hybridization: implications for monitoring patients with myelodysplastic syndrome and deletion 5q treated with lenalidomide.

Authors:  Gudrun Göhring; Aristoteles Giagounidis; Guntram Büsche; Winfried Hofmann; Hans Heinrich Kreipe; Pierre Fenaux; Eva Hellström-Lindberg; Brigitte Schlegelberger
Journal:  Haematologica       Date:  2010-11-25       Impact factor: 9.941

8.  Clinical utility of FISH analysis in addition to G-banded karyotype in hematologic malignancies and proposal of a practical approach.

Authors:  Won Kyung Kwon; Jin Young Lee; Yeung Chul Mun; Chu Myong Seong; Wha Soon Chung; Jungwon Huh
Journal:  Korean J Hematol       Date:  2010-09-30

9.  Serial assessment of suspected myelodysplastic syndromes: significance of flow cytometric findings validated by cytomorphology, cytogenetics, and molecular genetics.

Authors:  Wolfgang Kern; Claudia Haferlach; Susanne Schnittger; Tamara Alpermann; Torsten Haferlach
Journal:  Haematologica       Date:  2012-08-28       Impact factor: 9.941

10.  Subtype-specific patterns of molecular mutations in acute myeloid leukemia.

Authors:  D Rose; T Haferlach; S Schnittger; K Perglerová; W Kern; C Haferlach
Journal:  Leukemia       Date:  2016-06-10       Impact factor: 11.528
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