Literature DB >> 17309270

Direct C-arylation of beta-enamino esters and ketones with arynes.

Yeeman K Ramtohul1, Anik Chartrand.   

Abstract

An efficient, mild, and general method for the C-arylation of beta-enamino esters and ketones with arynes has been developed. This methodology provides a facile and direct access to a variety of substituted aromatic beta-enamino compounds in moderate to excellent yield. [reaction: see text]

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Year:  2007        PMID： 17309270     DOI： 10.1021/ol063057k

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  12 in total

1.  Direct Hiyama cross-coupling of enaminones with triethoxy(aryl)silanes and dimethylphenylsilanol.

Authors:  Lei Bi; Gunda I Georg
Journal:  Org Lett       Date:  2011-09-22       Impact factor: 6.005

2.  Steric effects compete with aryne distortion to control regioselectivities of nucleophilic additions to 3-silylarynes.

Authors:  Sarah M Bronner; Joel L Mackey; K N Houk; Neil K Garg
Journal:  J Am Chem Soc       Date:  2012-08-15       Impact factor: 15.419

3.  Synthesis of o-(dimethylamino)aryl ketones and acridones by the reaction of 1,1-dialkylhydrazones and arynes.

Authors:  Anton V Dubrovskiy; Richard C Larock
Journal:  Org Lett       Date:  2011-07-11       Impact factor: 6.005

4.  Overturning indolyne regioselectivities and synthesis of indolactam V.

Authors:  Sarah M Bronner; Adam E Goetz; Neil K Garg
Journal:  J Am Chem Soc       Date:  2011-02-25       Impact factor: 15.419

5.  Indolyne experimental and computational studies: synthetic applications and origins of selectivities of nucleophilic additions.

Authors:  G-Yoon J Im; Sarah M Bronner; Adam E Goetz; Robert S Paton; Paul H-Y Cheong; K N Houk; Neil K Garg
Journal:  J Am Chem Soc       Date:  2010-11-29       Impact factor: 15.419

6.  α-Functionalisation of Ketones Through Metal-Free Electrophilic Activation.

Authors:  Wojciech Zawodny; Christopher J Teskey; Magdalena Mishevska; Martin Völkl; Boris Maryasin; Leticia González; Nuno Maulide
Journal:  Angew Chem Int Ed Engl       Date:  2020-09-11       Impact factor: 15.336

7.  C-Arylation reactions catalyzed by CuO-nanoparticles under ligand free conditions.

Authors:  Mazaahir Kidwai; Saurav Bhardwaj; Roona Poddar
Journal:  Beilstein J Org Chem       Date:  2010-04-15       Impact factor: 2.883

8.  Enamide-benzyne-[2 + 2] cycloaddition: stereoselective tandem [2 + 2]-pericyclic ring-opening-intramolecular N-tethered [4 + 2] cycloadditions.

Authors:  John B Feltenberger; Ryuji Hayashi; Yu Tang; Eric S C Babiash; Richard P Hsung
Journal:  Org Lett       Date:  2009-08-20       Impact factor: 6.005

9.  Synthesis of o-(dimethylamino)aryl ketones, acridones, acridinium salts, and 1H-indazoles by the reaction of hydrazones and arynes.

Authors:  Anton V Dubrovskiy; Richard C Larock
Journal:  J Org Chem       Date:  2012-12-03       Impact factor: 4.354

10.  α-Arylation of Carbonyl Compounds through Oxidative C-C Bond Activation.

Authors:  Jing Li; Adriano Bauer; Giovanni Di Mauro; Nuno Maulide
Journal:  Angew Chem Int Ed Engl       Date:  2019-06-06       Impact factor: 16.823
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