Literature DB >> 17307360

Novel malonamide derivatives as potent kappa opioid receptor agonists.

Guo-Hua Chu1, Minghua Gu, Joel A Cassel, Serge Belanger, Thomas M Graczyk, Robert N DeHaven, Nathalie Conway-James, Michael Koblish, Patrick J Little, Diane L DeHaven-Hudkins, Roland E Dolle.   

Abstract

A novel series of malonamide derivatives was synthesized. These amides were shown to be potent and selective kappa opioid receptor agonists.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17307360     DOI： 10.1016/j.bmcl.2007.01.053

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  8 in total

1.  Computational and spectroscopic data correlation study of N,N'-bisarylmalonamides (Part II).

Authors:  Violeta M Arsovski; Bojan Đ Božić; Jelena M Mirković; Vesna D Vitnik; Željko J Vitnik; Slobodan D Petrović; Gordana S Ušćumlić; Dušan Ž Mijin
Journal:  J Mol Model       Date:  2015-08-21       Impact factor: 1.810

2.  Chemical function-based pharmacophore generation of selective kappa-opioid receptor agonists by catalyst and phase.

Authors:  Jing Zhang; Guixia Liu; Yun Tang
Journal:  J Mol Model       Date:  2009-02-11       Impact factor: 1.810

Review 3.  Kappa opioids and the modulation of pain.

Authors:  Bronwyn Kivell; Thomas E Prisinzano
Journal:  Psychopharmacology (Berl)       Date:  2010-04-07       Impact factor: 4.530

4.  Synthesis of novel series of malonamides derivatives via a five-component reaction.

Authors:  Abbas Rahmati; Tahmineh Kenarkoohi; Mahdi Ahmadi-Varzaneh
Journal:  Mol Divers       Date:  2013-05-24       Impact factor: 2.943

5.  Insights into subtype selectivity of opioid agonists by ligand-based and structure-based methods.

Authors:  Jianxin Cheng; Guixia Liu; Jing Zhang; Zhejun Xu; Yun Tang
Journal:  J Mol Model       Date:  2010-05-25       Impact factor: 1.810

6.  Antinociceptive potency of a fluorinated cyclopeptide Dmt-c[D-Lys-Phe-p-CF3-Phe-Asp]NH2.

Authors:  Justyna Piekielna-Ciesielska; Adriano Mollica; Stefano Pieretti; Jakub Fichna; Agata Szymaszkiewicz; Marta Zielińska; Radzisław Kordek; Anna Janecka
Journal:  J Enzyme Inhib Med Chem       Date:  2018-12       Impact factor: 5.051

7.  Metal-bio functionalized bismuthmagnetite [Fe3-x Bi x O4/SiO2@l-ArgEt3 +I-/Zn(ii)]: a novel bionanocomposite for the synthesis of 1,2,4,5-tetrahydro-2,4-dioxobenzo[b][1,4]diazepine malononitriles and malonamides at room temperature and under sonication.

Authors:  Fatemeh Molaei Yielzoleh; Kobra Nikoofar
Journal:  RSC Adv       Date:  2022-04-01       Impact factor: 3.361

8.  Synthesis, Crystal Structure and DFT Studies of a New Dinuclear Ag(I)-Malonamide Complex.

Authors:  Saied M Soliman; Assem Barakat; Mohammad Shahidul Islam; Hazem A Ghabbour
Journal:  Molecules       Date:  2018-04-11       Impact factor: 4.411
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.