Literature DB >> 17306909

Immunogenicity of novel consensus-based DNA vaccines against avian influenza.

Dominick J Laddy1, Jian Yan1, Natasha Corbitt1, Gary P Kobinger1, David B Weiner1.   

Abstract

The frequency of H5N1 avian influenza outbreaks in China and Eastern Europe has raised concern in the world health community regarding the potential for an influenza pandemic. Efforts to monitor the disease will only provide minimal warning in a global society, and steps must be taken to prevent the morbidity and mortality associated with past pandemics. The current stockpiling of antibody-inducing "bird flu" vaccines assumes the strain that emerges will be the same as strains currently circulating. We propose a novel consensus-based approach to vaccine development, employing a DNA vaccine strategy that can provide more highly cross-reactive cellular immunity against lethal influenza infection. We show such constructs can induce strong cellular immunity against H5 influenza antigens.

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Year:  2007        PMID： 17306909      PMCID： PMC4477802          DOI： 10.1016/j.vaccine.2007.01.063

Source DB:  PubMed          Journal:  Vaccine        ISSN： 0264-410X            Impact factor:   3.641


  25 in total

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Journal:  J Virol       Date:  2000-08       Impact factor: 5.103

2.  The hypervariable immunodominant NP418-426 epitope from the influenza A virus nucleoprotein is recognized by cytotoxic T lymphocytes with high functional avidity.

Authors:  Adrianus C M Boon; Gerrie de Mutsert; Ron A M Fouchier; Albert D M E Osterhaus; Guus F Rimmelzwaan
Journal:  J Virol       Date:  2006-06       Impact factor: 5.103

3.  Induction of potent Th1-type immune responses from a novel DNA vaccine for West Nile virus New York isolate (WNV-NY1999).

Authors:  J S Yang; J J Kim; D Hwang; A Y Choo; K Dang; H Maguire; S Kudchodkar; M P Ramanathan; D B Weiner
Journal:  J Infect Dis       Date:  2001-08-29       Impact factor: 5.226

4.  Introduction to pandemic influenza through history.

Authors:  Y Ghendon
Journal:  Eur J Epidemiol       Date:  1994-08       Impact factor: 8.082

5.  Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help.

Authors:  Michele A Kutzler; Tara M Robinson; Michael A Chattergoon; Daniel K Choo; Andrew Y Choo; Philip Y Choe; Mathura P Ramanathan; Rose Parkinson; Sagar Kudchodkar; Yutaka Tamura; Maninder Sidhu; Vidia Roopchand; J Joseph Kim; George N Pavlakis; Barbara K Felber; Thomas A Waldmann; Jean D Boyer; David B Weiner
Journal:  J Immunol       Date:  2005-07-01       Impact factor: 5.422

6.  Cross-clade protection induced by human immunodeficiency virus-1 DNA immunogens expressing consensus sequences of multiple genes and epitopes from subtypes A, B, C, and FGH.

Authors:  Maria Malm; Erik Rollman; Mart Ustav; Jorma Hinkula; Kai Krohn; Britta Wahren; Vesna Blazevic
Journal:  Viral Immunol       Date:  2005       Impact factor: 2.257

7.  Primary influenza A virus infection induces cross-protective immunity against a lethal infection with a heterosubtypic virus strain in mice.

Authors:  J H C M Kreijtz; R Bodewes; G van Amerongen; T Kuiken; R A M Fouchier; A D M E Osterhaus; G F Rimmelzwaan
Journal:  Vaccine       Date:  2006-09-07       Impact factor: 3.641

8.  Immunogenicity testing of a novel engineered HIV-1 envelope gp140 DNA vaccine construct.

Authors:  Sanjeev Kumar; Jian Yan; Karuppiah Muthumani; Mathura P Ramanathan; Hanna Yoon; George N Pavlakis; Barbara K Felber; Maninder Sidhu; Jean D Boyer; David B Weiner
Journal:  DNA Cell Biol       Date:  2006-07       Impact factor: 3.311

Review 9.  Source for influenza pandemics.

Authors:  C Scholtissek
Journal:  Eur J Epidemiol       Date:  1994-08       Impact factor: 8.082

10.  Mutations in the cytoplasmic domain of the influenza virus hemagglutinin affect different stages of intracellular transport.

Authors:  C Doyle; M G Roth; J Sambrook; M J Gething
Journal:  J Cell Biol       Date:  1985-03       Impact factor: 10.539
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  49 in total

1.  Feasibility of reconstructed ancestral H5N1 influenza viruses for cross-clade protective vaccine development.

Authors:  Mariette F Ducatez; Justin Bahl; Yolanda Griffin; Evelyn Stigger-Rosser; John Franks; Subrata Barman; Dhanasekaran Vijaykrishna; Ashley Webb; Yi Guan; Robert G Webster; Gavin J D Smith; Richard J Webby
Journal:  Proc Natl Acad Sci U S A       Date:  2010-12-20       Impact factor: 11.205

Review 2.  The threat of avian influenza A (H5N1). Part IV: Development of vaccines.

Authors:  Jindrich Cinatl; Martin Michaelis; Hans W Doerr
Journal:  Med Microbiol Immunol       Date:  2007-06-01       Impact factor: 3.402

Review 3.  DNA vaccines: developing new strategies to enhance immune responses.

Authors:  Shaheed A Abdulhaqq; David B Weiner
Journal:  Immunol Res       Date:  2008       Impact factor: 2.829

4.  DNA plasmid production in different host strains of Escherichia coli.

Authors:  Adam Singer; Mark A Eiteman; Elliot Altman
Journal:  J Ind Microbiol Biotechnol       Date:  2009-01-10       Impact factor: 3.346

5.  A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses.

Authors:  Ming-Wei Chen; Ting-Jen Rachel Cheng; Yaoxing Huang; Jia-Tsrong Jan; Shiou-Hwa Ma; Alice L Yu; Chi-Huey Wong; David D Ho
Journal:  Proc Natl Acad Sci U S A       Date:  2008-09-02       Impact factor: 11.205

6.  Novel linear DNA vaccines induce protective immune responses against lethal infection with influenza virus type A/H5N1.

Authors:  Frédéric Kendirgi; Nadezda E Yun; Nathaniel S Linde; Michele A Zacks; Jeanon N Smith; Jennifer K Smith; Harilyn McMicken; Yin Chen; Slobodan Paessler
Journal:  Hum Vaccin       Date:  2008-11-21

7.  Multivalent TB vaccines targeting the esx gene family generate potent and broad cell-mediated immune responses superior to BCG.

Authors:  Daniel O Villarreal; Jewell Walters; Dominick J Laddy; Jian Yan; David B Weiner
Journal:  Hum Vaccin Immunother       Date:  2014       Impact factor: 3.452

Review 8.  Plasmid DNA vaccine vector design: impact on efficacy, safety and upstream production.

Authors:  James A Williams; Aaron E Carnes; Clague P Hodgson
Journal:  Biotechnol Adv       Date:  2009-02-20       Impact factor: 14.227

9.  Cellular immunity induced by a novel HPV18 DNA vaccine encoding an E6/E7 fusion consensus protein in mice and rhesus macaques.

Authors:  Jian Yan; Kristina Harris; Amir S Khan; Ruxandra Draghia-Akli; Duane Sewell; David B Weiner
Journal:  Vaccine       Date:  2008-04-14       Impact factor: 3.641

10.  Two novel HLA-A*0201 T-cell epitopes in avian H5N1 viral nucleoprotein induced specific immune responses in HHD mice.

Authors:  Ying-Kit Cheung; Samuel Chak-Sum Cheng; Yan Ke; Yong Xie
Journal:  Vet Res       Date:  2009-11-27       Impact factor: 3.683
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