Literature DB >> 17306511

TRPML and lysosomal function.

David A Zeevi1, Ayala Frumkin, Gideon Bach.   

Abstract

Mucolipin 1 (MLN1), also known as TRPML1, is a member of the mucolipin family. The mucolipins are the only lysosomal proteins within the TRP superfamily. Mutations in the gene coding for TRPML1 result in a lysosomal storage disorder (LSD). This review summarizes the current knowledge related to this protein and the rest of the mucolipin family.

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Year:  2007        PMID： 17306511     DOI： 10.1016/j.bbadis.2007.01.004

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  40 in total

1.  Heteromultimeric TRPML channel assemblies play a crucial role in the regulation of cell viability models and starvation-induced autophagy.

Authors:  David A Zeevi; Shaya Lev; Ayala Frumkin; Baruch Minke; Gideon Bach
Journal:  J Cell Sci       Date:  2010-08-24       Impact factor: 5.285

2.  The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel.

Authors:  Xian-Ping Dong; Xiping Cheng; Eric Mills; Markus Delling; Fudi Wang; Tino Kurz; Haoxing Xu
Journal:  Nature       Date:  2008-09-14       Impact factor: 49.962

Review 3.  TRPML: transporters of metals in lysosomes essential for cell survival?

Authors:  Kirill Kiselyov; Grace A Colletti; Austen Terwilliger; Kathleen Ketchum; Christopher W P Lyons; James Quinn; Shmuel Muallem
Journal:  Cell Calcium       Date:  2011-05-31       Impact factor: 6.817

Review 4.  Transient receptor potential channelopathies.

Authors:  Bernd Nilius; Grzegorz Owsianik
Journal:  Pflugers Arch       Date:  2010-02-04       Impact factor: 3.657

Review 5.  Evolutionary dynamics of metazoan TRP channels.

Authors:  Tatsuhiko Kadowaki
Journal:  Pflugers Arch       Date:  2015-04-01       Impact factor: 3.657

6.  Expression and vesicular localization of mouse Trpml3 in stria vascularis, hair cells, and vomeronasal and olfactory receptor neurons.

Authors:  Andrew J Castiglioni; Natalie N Remis; Emma N Flores; Jaime García-Añoveros
Journal:  J Comp Neurol       Date:  2011-04-15       Impact factor: 3.215

Review 7.  The regulatory mechanism of mammalian TRPMLs revealed by cryo-EM.

Authors:  Philip Schmiege; Michael Fine; Xiaochun Li
Journal:  FEBS J       Date:  2018-04-14       Impact factor: 5.542

8.  Activating mutation in a mucolipin transient receptor potential channel leads to melanocyte loss in varitint-waddler mice.

Authors:  Haoxing Xu; Markus Delling; Linyu Li; Xianping Dong; David E Clapham
Journal:  Proc Natl Acad Sci U S A       Date:  2007-11-07       Impact factor: 11.205

9.  Constitutive activity of the human TRPML2 channel induces cell degeneration.

Authors:  Shaya Lev; David A Zeevi; Ayala Frumkin; Vered Offen-Glasner; Gideon Bach; Baruch Minke
Journal:  J Biol Chem       Date:  2009-11-23       Impact factor: 5.157

10.  The tissue-specific expression of TRPML2 (MCOLN-2) gene is influenced by the presence of TRPML1.

Authors:  Mohammad A Samie; Christian Grimm; Jeffrey A Evans; Cyntia Curcio-Morelli; Stefan Heller; Susan A Slaugenhaupt; Math P Cuajungco
Journal:  Pflugers Arch       Date:  2009-11       Impact factor: 3.657
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