OBJECTIVE: The purpose of the study was to determine whether exercise-induced increases in energy expenditure (EE) alter circulating leptin levels in obese individuals. DESIGN: Participants were randomized to an exercise intervention group (n = 8) or nonexercising control (n = 7). SETTING: All data were collected on an outpatient basis at the exercise physiology laboratory at the University of Central Florida. PATIENTS: Fifteen healthy obese males (24.9 +/- 1.4 years old, body mass index 33.4 +/- 0.7 kg . m). INTERVENTIONS: Members of the intervention group underwent a single exercise session of moderate intensity (58.4 +/- 1.3% of VO2max) for 60 minutes. MAIN OUTCOME MEASUREMENTS: Postexercise, 24 hour postexercise, and 48 hour postexercise levels of leptin, insulin, and ghrelin. RESULTS: The exercise session elicited an EE of 567 +/- 25 Kcal. No significant main effect or time-by-group interactions for leptin or ghrelin were observed immediately after the exercise bout or in the days following the intervention. CONCLUSIONS: These preliminary data suggest that a bout of acute exercise of moderate intensity and duration does not affect leptin concentration. It is possible that a higher level of EE is required to elicit substantial changes.
RCT Entities:
OBJECTIVE: The purpose of the study was to determine whether exercise-induced increases in energy expenditure (EE) alter circulating leptin levels in obese individuals. DESIGN:Participants were randomized to an exercise intervention group (n = 8) or nonexercising control (n = 7). SETTING: All data were collected on an outpatient basis at the exercise physiology laboratory at the University of Central Florida. PATIENTS: Fifteen healthy obese males (24.9 +/- 1.4 years old, body mass index 33.4 +/- 0.7 kg . m). INTERVENTIONS: Members of the intervention group underwent a single exercise session of moderate intensity (58.4 +/- 1.3% of VO2max) for 60 minutes. MAIN OUTCOME MEASUREMENTS: Postexercise, 24 hour postexercise, and 48 hour postexercise levels of leptin, insulin, and ghrelin. RESULTS: The exercise session elicited an EE of 567 +/- 25 Kcal. No significant main effect or time-by-group interactions for leptin or ghrelin were observed immediately after the exercise bout or in the days following the intervention. CONCLUSIONS: These preliminary data suggest that a bout of acute exercise of moderate intensity and duration does not affect leptin concentration. It is possible that a higher level of EE is required to elicit substantial changes.
Authors: A E Rigamonti; F Agosti; A De Col; N Marazzi; C L Lafortuna; S G Cella; E E Muller; A Sartorio Journal: J Endocrinol Invest Date: 2010-03-25 Impact factor: 4.256
Authors: Todd A Hagobian; Carrie G Sharoff; Brooke R Stephens; George N Wade; J Enrique Silva; Stuart R Chipkin; Barry Braun Journal: Am J Physiol Regul Integr Comp Physiol Date: 2008-12-10 Impact factor: 3.619
Authors: Ayse Alp; Sadik Buyukbas; Harun Alp; H Serdar Gergerlioglu; Mehmet Oz; M Kemal Basarali; Aysel Kiyici Journal: J Sports Sci Med Date: 2011-12-01 Impact factor: 2.988