Literature DB >> 17303692

Moderation of the platelet releasate response by aspirin.

Judith A Coppinger1, Roisin O'Connor, Kieran Wynne, Michelle Flanagan, Matthew Sullivan, Patricia B Maguire, Desmond J Fitzgerald, Gerard Cagney.   

Abstract

Modulation of the proteins released during activation is one mechanism whereby aspirin may influence platelet-mediated human disease. We investigated the effect of aspirin on the platelet releasate using mass spectrometry and found that different agonists evoked different releasate profiles, with aspirin having a general moderating effect on the amount of protein released regardless of the agonist. These observations were confirmed for several cytokines using an antibody array approach.

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Year:  2007        PMID: 17303692     DOI: 10.1182/blood-2006-07-038539

Source DB:  PubMed          Journal:  Blood        ISSN: 0006-4971            Impact factor:   22.113


  48 in total

1.  Internalization of IgG-coated targets results in activation and secretion of soluble CD40 ligand and RANTES by human platelets.

Authors:  Adam J Antczak; Joshua A Vieth; Navinderjit Singh; Randall G Worth
Journal:  Clin Vaccine Immunol       Date:  2010-12-22

2.  Platelet-mediated angiogenesis is independent of VEGF and fully inhibited by aspirin.

Authors:  J Etulain; C Fondevila; S Negrotto; M Schattner
Journal:  Br J Pharmacol       Date:  2013-09       Impact factor: 8.739

Review 3.  Platelets and the immune continuum.

Authors:  John W Semple; Joseph E Italiano; John Freedman
Journal:  Nat Rev Immunol       Date:  2011-04       Impact factor: 53.106

4.  Aspirin inhibits platelets from reprogramming breast tumor cells and promoting metastasis.

Authors:  Kelly E Johnson; Julia R Ceglowski; Harvey G Roweth; Jodi A Forward; Mason D Tippy; Saleh El-Husayni; Rajesh Kulenthirarajan; Michael W Malloy; Kellie R Machlus; Wendy Y Chen; Joseph E Italiano; Elisabeth M Battinelli
Journal:  Blood Adv       Date:  2019-01-22

5.  Sulfasalazine and its metabolites inhibit platelet function in patients with inflammatory arthritis.

Authors:  Paul A MacMullan; Anne M Madigan; Nevin Paul; Aaron J Peace; Ahmed Alagha; Kevin B Nolan; Geraldine M McCarthy; Dermot Kenny
Journal:  Clin Rheumatol       Date:  2014-09-26       Impact factor: 2.980

6.  Effects of celecoxib on prostanoid biosynthesis and circulating angiogenesis proteins in familial adenomatous polyposis.

Authors:  Melania Dovizio; Stefania Tacconelli; Emanuela Ricciotti; Annalisa Bruno; Thorsten Jürgen Maier; Paola Anzellotti; Luigia Di Francesco; Paola Sala; Stefano Signoroni; Lucio Bertario; Dan A Dixon; John A Lawson; Dieter Steinhilber; Garret A FitzGerald; Paola Patrignani
Journal:  J Pharmacol Exp Ther       Date:  2012-01-19       Impact factor: 4.030

7.  Activated platelets enhance ovarian cancer cell invasion in a cellular model of metastasis.

Authors:  C E Holmes; J E Levis; D L Ornstein
Journal:  Clin Exp Metastasis       Date:  2009-05-15       Impact factor: 5.150

8.  IκB kinase phosphorylation of SNAP-23 controls platelet secretion.

Authors:  Zubair A Karim; Jinchao Zhang; Meenakshi Banerjee; Michael C Chicka; Rania Al Hawas; Tara R Hamilton; Paul A Roche; Sidney W Whiteheart
Journal:  Blood       Date:  2013-04-23       Impact factor: 22.113

9.  Proteomics strategy for identifying candidate bioactive proteins in complex mixtures: application to the platelet releasate.

Authors:  Roisin O'Connor; Lorna M Cryan; Kieran Wynne; Andreas de Stefani; Desmond Fitzgerald; Colm O'Brien; Gerard Cagney
Journal:  J Biomed Biotechnol       Date:  2010-03-24

10.  Platelet glycoproteins associated with aspirin-treatment upon platelet activation.

Authors:  Punit Shah; Weiming Yang; Shisheng Sun; Jered Pasay; Nauder Faraday; Hui Zhang
Journal:  Proteomics       Date:  2016-09-12       Impact factor: 3.984

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