| Literature DB >> 17303399 |
Renée de Pooter1, Juan Carlos Zúñiga-Pflücker.
Abstract
In vivo, T cells develop in the thymus from bone marrow-derived hematopoietic progenitors. Similarly, T cells can develop in vitro in model systems that mimic thymic function. The recent development of the OP9-DL1 cell culture system, a two-dimensional T-inductive environment, has provided greater access to the processes of commitment and development in T lymphocytes.Mesh：
Year: 2007 PMID： 17303399 DOI： 10.1016/j.coi.2007.02.011
Source DB: PubMed Journal: Curr Opin Immunol ISSN： 0952-7915 Impact factor: 7.486