Literature DB >> 1730255

Liposome-mediated delivery stimulates a class I-restricted cytotoxic T cell response to soluble antigen.

L M Lopes1, B M Chain.   

Abstract

Most soluble protein antigens are poor at priming class I-restricted cytotoxic cell activity. In this study we show that incorporation of one protein, ovalbumin, into liposomes converts this antigen into an effective stimulator of antigen-specific cytotoxicity. The mechanisms responsible for this phenomenon are discussed.

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Year:  1992        PMID： 1730255     DOI： 10.1002/eji.1830220143

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN： 0014-2980            Impact factor:   5.532


  6 in total

1.  Liposomes containing lipid A serve as an adjuvant for induction of antibody and cytotoxic T-cell responses against RTS,S malaria antigen.

Authors:  R L Richards; M Rao; N M Wassef; G M Glenn; S W Rothwell; C R Alving
Journal:  Infect Immun       Date:  1998-06       Impact factor: 3.441

2.  The demonstration of an essential role for macrophages in the in vivo generation of IgG2a antibodies.

Authors:  J M Brewer; J Richmond; J Alexander
Journal:  Clin Exp Immunol       Date:  1994-07       Impact factor: 4.330

3.  Antibody and cytotoxic T-cell responses to soluble hepatitis B virus (HBV) S antigen in mice: implication for the pathogenesis of HBV-induced hepatitis.

Authors:  R Schirmbeck; K Melber; T Mertens; J Reimann
Journal:  J Virol       Date:  1994-03       Impact factor: 5.103

4.  Epstein-Barr virus-transformed B cells, a potentially convenient source of autologous antigen-presenting cells for the propagation of certain human cytotoxic T lymphocytes.

Authors:  M B Purner; R L Berens; E C Krug; T J Curiel
Journal:  Clin Diagn Lab Immunol       Date:  1994-11

5.  Cationic lipids direct a viral glycoprotein into the class I major histocompatibility complex antigen-presentation pathway.

Authors:  C Walker; M Selby; A Erickson; D Cataldo; J P Valensi; G V Van Nest
Journal:  Proc Natl Acad Sci U S A       Date:  1992-09-01       Impact factor: 11.205

Review 6.  Attacking the Intruder at the Gate: Prospects of Mucosal Anti SARS-CoV-2 Vaccines.

Authors:  Kacper Karczmarzyk; Małgorzata Kęsik-Brodacka
Journal:  Pathogens       Date:  2022-01-19
  6 in total

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