AIM OF THE STUDY: To investigate the seroprevalence of Helicobacter pylori infection in young children from the general population in The Netherlands. METHODS: Determination of IgG antibodies against H. pylori, using an enzyme-linked immunosorbent assay technique [cutoff 0.32 Absorption Index (AI)], in serum from 1258 children who were 2-4 years of age. The serum was obtained from a serum bank of 6127 children who attended the community child healthcare centers in the Dutch province of Zuid-Holland. RESULTS: In general, we found a seroprevalence of 1.2% of H. pylori infection, with a significant difference between the children with parents who were both Dutch (0.5%), and the children with at least one non-Dutch parent (2.6%) (P<0.001). CONCLUSIONS: The prevalence of H. pylori infection in young infants in the general population in The Netherlands is low. Children with at least one non-Dutch parent form a risk group, however, for H. pylori infection in The Netherlands.
AIM OF THE STUDY: To investigate the seroprevalence of Helicobacter pyloriinfection in young children from the general population in The Netherlands. METHODS: Determination of IgG antibodies against H. pylori, using an enzyme-linked immunosorbent assay technique [cutoff 0.32 Absorption Index (AI)], in serum from 1258 children who were 2-4 years of age. The serum was obtained from a serum bank of 6127 children who attended the community child healthcare centers in the Dutch province of Zuid-Holland. RESULTS: In general, we found a seroprevalence of 1.2% of H. pyloriinfection, with a significant difference between the children with parents who were both Dutch (0.5%), and the children with at least one non-Dutch parent (2.6%) (P<0.001). CONCLUSIONS: The prevalence of H. pyloriinfection in young infants in the general population in The Netherlands is low. Children with at least one non-Dutch parent form a risk group, however, for H. pyloriinfection in The Netherlands.
Authors: Caroline M den Hoed; Anne J Vila; Ingrid L Holster; Guillermo I Perez-Perez; Martin J Blaser; Johan C de Jongste; Ernest J Kuipers Journal: Helicobacter Date: 2011-10 Impact factor: 5.753
Authors: T van den Bruele; P E C Mourad-Baars; E C J Claas; R N van der Plas; E J Kuijper; R G M Bredius Journal: Eur J Clin Microbiol Infect Dis Date: 2010-06-17 Impact factor: 3.267
Authors: A C de Vries; G A Meijer; C W N Looman; M K Casparie; B E Hansen; N C T van Grieken; E J Kuipers Journal: Gut Date: 2007-08-14 Impact factor: 23.059