BACKGROUND: We aimed to assess the point prevalence of microalbuminuria (MAU) in a sample of unselected consecutive primary-care attendees, with particular focus on patients with diabetes mellitus (with and without additional concomitant diseases) and those with hypertension. DESIGN: Cross-sectional observational study in a nationwide representative sample of 1912 primary-care practices and a patient population consisting of 39 125 primary-care attendees. Diagnoses for diabetes, hypertension and co-morbidities were provided by the treating physician and complemented by blood pressure (BP) measurements and selected lab tests. Screening for microalbuminuria (>20 and <200 microg/ml) was done with a spot urine dipstick test. RESULTS: The clinical diagnosis of nephropathy was assigned to 7.6% of patients. The point prevalence of MAU was 19.0% in the total sample; the proportion was 33.6% in diabetics whereas the diagnosis was assigned to only 7.1% in the total sample. Amongst diabetic patients with MAU, 92.6% had BP above the target value of <130/80 mmHg. Frequency rates rose with increasing BP (e.g. 20.6% in diabetic patients with BP<120/70 mmHg, and 36.3% in diabetic patients with BP>140/90 mmHg). Of note, patients with MAU had a higher burden of co-morbidity compared to those without MAU. CONCLUSIONS: We found a high prevalence of MAU in primary care, particularly in diabetic patients. The frequency of MAU was closely related to the BP level and the degree of co-morbidity. The present study underlines the magnitude of the problem of MAU in primary care, and should serve as a starting point to initiate measures to address this important public health issue.
BACKGROUND: We aimed to assess the point prevalence of microalbuminuria (MAU) in a sample of unselected consecutive primary-care attendees, with particular focus on patients with diabetes mellitus (with and without additional concomitant diseases) and those with hypertension. DESIGN: Cross-sectional observational study in a nationwide representative sample of 1912 primary-care practices and a patient population consisting of 39 125 primary-care attendees. Diagnoses for diabetes, hypertension and co-morbidities were provided by the treating physician and complemented by blood pressure (BP) measurements and selected lab tests. Screening for microalbuminuria (>20 and <200 microg/ml) was done with a spot urine dipstick test. RESULTS: The clinical diagnosis of nephropathy was assigned to 7.6% of patients. The point prevalence of MAU was 19.0% in the total sample; the proportion was 33.6% in diabetics whereas the diagnosis was assigned to only 7.1% in the total sample. Amongst diabeticpatients with MAU, 92.6% had BP above the target value of <130/80 mmHg. Frequency rates rose with increasing BP (e.g. 20.6% in diabeticpatients with BP<120/70 mmHg, and 36.3% in diabeticpatients with BP>140/90 mmHg). Of note, patients with MAU had a higher burden of co-morbidity compared to those without MAU. CONCLUSIONS: We found a high prevalence of MAU in primary care, particularly in diabeticpatients. The frequency of MAU was closely related to the BP level and the degree of co-morbidity. The present study underlines the magnitude of the problem of MAU in primary care, and should serve as a starting point to initiate measures to address this important public health issue.
Authors: Martin Thoenes; Peter Bramlage; Pepe Zamorano; David Messika-Zeitoun; Daniel Wendt; Markus Kasel; Jana Kurucova; Richard P Steeds Journal: J Thorac Dis Date: 2018-09 Impact factor: 2.895
Authors: Michael Böhm; Adriaan A Voors; Jean-Marie Ketelslegers; Stephan H Schirmer; Eva Turgonyi; Peter Bramlage; Faiez Zannad Journal: Clin Res Cardiol Date: 2011-07-16 Impact factor: 5.460
Authors: Roland E Schmieder; Stephan Martin; Gabriele E Lang; Peter Bramlage; Michael Böhm Journal: Dtsch Arztebl Int Date: 2009-08-24 Impact factor: 5.594