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Literature DB >> 17301484

Putting T cells to sleep: a new paradigm for immune evasion by persistent viruses.

Shweta Dubey¹, Shahid Jameel.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 2006 PMID： 17301484 DOI： 10.1007/BF02708398

Source DB: PubMed Journal: J Biosci ISSN： 0250-5991 Impact factor: 2.795

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17 in total

1. PD-L1 is induced in hepatocytes by viral infection and by interferon-alpha and -gamma and mediates T cell apoptosis.

Authors: Marcus Mühlbauer; Martin Fleck; Christian Schütz; Thomas Weiss; Matthias Froh; Christian Blank; Jürgen Schölmerich; Claus Hellerbrand
Journal: J Hepatol Date: 2006-06-16 Impact factor: 25.083

2. Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction.

Authors: Lydie Trautmann; Loury Janbazian; Nicolas Chomont; Elias A Said; Sylvain Gimmig; Benoit Bessette; Mohamed-Rachid Boulassel; Eric Delwart; Homero Sepulveda; Robert S Balderas; Jean-Pierre Routy; Elias K Haddad; Rafick-Pierre Sekaly
Journal: Nat Med Date: 2006-08-20 Impact factor: 53.440

3. Expression of B7-H1 and B7-DC on the airway epithelium is enhanced by double-stranded RNA.

Authors: Miyuki Tsuda; Koichiro Matsumoto; Hiromasa Inoue; Mikiko Matsumura; Takako Nakano; Akio Mori; Miyuki Azuma; Yoichi Nakanishi
Journal: Biochem Biophys Res Commun Date: 2005-04-29 Impact factor: 3.575

4. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression.

Authors: Cheryl L Day; Daniel E Kaufmann; Photini Kiepiela; Julia A Brown; Eshia S Moodley; Sharon Reddy; Elizabeth W Mackey; Joseph D Miller; Alasdair J Leslie; Chantal DePierres; Zenele Mncube; Jaikumar Duraiswamy; Baogong Zhu; Quentin Eichbaum; Marcus Altfeld; E John Wherry; Hoosen M Coovadia; Philip J R Goulder; Paul Klenerman; Rafi Ahmed; Gordon J Freeman; Bruce D Walker
Journal: Nature Date: 2006-08-20 Impact factor: 49.962

Putting T cells to sleep: a new paradigm for immune evasion by persistent viruses.

1. PD-L1 is induced in hepatocytes by viral infection and by interferon-alpha and -gamma and mediates T cell apoptosis.

2. Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction.

3. Expression of B7-H1 and B7-DC on the airway epithelium is enhanced by double-stranded RNA.

4. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression.

5. PD-1 expression in acute hepatitis C virus (HCV) infection is associated with HCV-specific CD8 exhaustion.

6. Restoring function in exhausted CD8 T cells during chronic viral infection.

7. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion.

8. Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade.

9. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.

10. PD-1 inhibits antiviral immunity at the effector phase in the liver.

1. The influence of CD4+ CD25+ Foxp3+ regulatory T cells on the immune response to rotavirus infection.