Literature DB >> 17301118

Retinal nerve fibre thickness measured with optical coherence tomography accurately detects confirmed glaucomatous damage.

D C Hood1, N Harizman, F N Kanadani, T M Grippo, S Baharestani, V C Greenstein, J M Liebmann, R Ritch.   

Abstract

AIM: To assess the accuracy of optical coherence tomography (OCT) in detecting damage to a hemifield, patients with hemifield defects confirmed on both static automated perimetry (SAP) and multifocal visual evoked potentials (mfVEP) were studied.
METHODS: Eyes of 40 patients with concomitant SAP and mfVEP glaucomatous loss and 25 controls underwent OCT retinal nerve fibre layer (RNFL), mfVEP and 24-2 SAP tests. For the mfVEP and 24-2 SAP, a hemifield was defined as abnormal based upon cluster criteria. On OCT, a hemifield was considered abnormal if one of the five clock hour sectors (3 and 9 o'clock excluded) was at <1% (red) or two were at <5% (yellow).
RESULTS: Seventy seven (43%) of the hemifields were abnormal on both mfVEP and SAP tests. The OCT was abnormal for 73 (95%) of these. Only 1 (1%) of the 100 hemifields of the controls was abnormal on OCT. Sensitivity/specificity (one eye per person) was 95/98%.
CONCLUSIONS: The OCT RNFL test accurately detects abnormal hemifields confirmed on both subjective and objective functional tests. Identifying abnormal hemifields with a criterion of 1 red (1%) or 2 yellow (5%) clock hours may prove useful in clinical practice.

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Year:  2007        PMID: 17301118      PMCID: PMC1955668          DOI: 10.1136/bjo.2006.111252

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  19 in total

Review 1.  Multifocal VEP and ganglion cell damage: applications and limitations for the study of glaucoma.

Authors:  Donald C Hood; Vivienne C Greenstein
Journal:  Prog Retin Eye Res       Date:  2003-03       Impact factor: 21.198

2.  Detecting early to mild glaucomatous damage: a comparison of the multifocal VEP and automated perimetry.

Authors:  Donald C Hood; Phamornsak Thienprasiddhi; Vivienne C Greenstein; Bryan J Winn; Nitin Ohri; Jeffrey M Liebmann; Robert Ritch
Journal:  Invest Ophthalmol Vis Sci       Date:  2004-02       Impact factor: 4.799

3.  Comparison of analytic algorithms for detecting glaucomatous visual field loss.

Authors:  J Katz; A Sommer; D E Gaasterland; D R Anderson
Journal:  Arch Ophthalmol       Date:  1991-12

4.  Cluster analysis in visual field quantification.

Authors:  B C Chauhan; D B Henson; A J Hobley
Journal:  Doc Ophthalmol       Date:  1988-05       Impact factor: 2.379

5.  Comparison of three optical coherence tomography scanning areas for detection of glaucomatous damage.

Authors:  Gadi Wollstein; Hiroshi Ishikawa; Jiping Wang; Siobahn A Beaton; Joel S Schuman
Journal:  Am J Ophthalmol       Date:  2005-01       Impact factor: 5.258

6.  Number of ganglion cells in glaucoma eyes compared with threshold visual field tests in the same persons.

Authors:  L A Kerrigan-Baumrind; H A Quigley; M E Pease; D F Kerrigan; R S Mitchell
Journal:  Invest Ophthalmol Vis Sci       Date:  2000-03       Impact factor: 4.799

7.  A comparison of optical coherence tomography and retinal nerve fiber layer photography for detection of nerve fiber layer damage in glaucoma.

Authors:  L M Zangwill; J Williams; C C Berry; S Knauer; R N Weinreb
Journal:  Ophthalmology       Date:  2000-07       Impact factor: 12.079

8.  Using optical imaging summary data to detect glaucoma.

Authors:  C Sanchez-Galeana; C Bowd; E Z Blumenthal; P A Gokhale; L M Zangwill; R N Weinreb
Journal:  Ophthalmology       Date:  2001-10       Impact factor: 12.079

9.  Sensitivity and specificity of the StratusOCT for perimetric glaucoma.

Authors:  Donald L Budenz; Anika Michael; Robert T Chang; John McSoley; Joanne Katz
Journal:  Ophthalmology       Date:  2005-01       Impact factor: 12.079

10.  Identifying early glaucoma with optical coherence tomography.

Authors:  Kouros Nouri-Mahdavi; Douglas Hoffman; Dana P Tannenbaum; Simon K Law; Joseph Caprioli
Journal:  Am J Ophthalmol       Date:  2004-02       Impact factor: 5.258

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  12 in total

1.  Understanding disparities among diagnostic technologies in glaucoma.

Authors:  Carlos Gustavo V De Moraes; Jeffrey M Liebmann; Robert Ritch; Donald C Hood
Journal:  Arch Ophthalmol       Date:  2012-07

2.  Optical coherence tomography for clinical detection and monitoring of glaucoma?

Authors:  Christopher Bowd
Journal:  Br J Ophthalmol       Date:  2007-07       Impact factor: 4.638

3.  Structural and functional changes in glaucoma: comparing the two-flash multifocal electroretinogram to optical coherence tomography and visual fields.

Authors:  Anna A Ledolter; Matthias Monhart; Andreas Schoetzau; Margarita G Todorova; Anja M Palmowski-Wolfe
Journal:  Doc Ophthalmol       Date:  2015-01-24       Impact factor: 2.379

4.  Clinical use of multifocal visual-evoked potentials in a glaucoma practice: a prospective study.

Authors:  Carlos Gustavo De Moraes; Jeffrey M Liebmann; Robert Ritch; Donald C Hood
Journal:  Doc Ophthalmol       Date:  2012-04-05       Impact factor: 2.379

5.  The location of the inferior and superior temporal blood vessels and interindividual variability of the retinal nerve fiber layer thickness.

Authors:  Donald C Hood; Jennifer A Salant; Stella N Arthur; Robert Ritch; Jeffrey M Liebmann
Journal:  J Glaucoma       Date:  2010-03       Impact factor: 2.503

6.  Comparative studies of RNFL thickness measured by OCT with global index of visual fields in patients with ocular hypertension and early open angle glaucoma.

Authors:  Sergios Taliantzis; Dimitris Papaconstantinou; Chrysanthi Koutsandrea; Michalis Moschos; Michalis Apostolopoulos; Gerasimos Georgopoulos
Journal:  Clin Ophthalmol       Date:  2009-06-29

7.  First-visit diagnosis of preperimetric glaucoma.

Authors:  Avinoam Ophir
Journal:  Open Ophthalmol J       Date:  2010-05-31

8.  An analysis of normal variations in retinal nerve fiber layer thickness profiles measured with optical coherence tomography.

Authors:  Quraish Ghadiali; Donald C Hood; Clara Lee; Jack Manns; Alex Llinas; Larissa K Grover; Vivienne C Greenstein; Jeffrey M Liebmann; Jeffrey G Odel; Robert Ritch
Journal:  J Glaucoma       Date:  2008-08       Impact factor: 2.503

9.  Central Glaucomatous Damage of the Macula Can Be Overlooked by Conventional OCT Retinal Nerve Fiber Layer Thickness Analyses.

Authors:  Diane L Wang; Ali S Raza; Carlos Gustavo de Moraes; Monica Chen; Paula Alhadeff; Ravivarn Jarukatsetphorn; Robert Ritch; Donald C Hood
Journal:  Transl Vis Sci Technol       Date:  2015-11-30       Impact factor: 3.283

10.  Differentiating glaucomatous from non-glaucomatous optic nerve cupping by optical coherence tomography.

Authors:  Preeya K Gupta; Sanjay Asrani; Sharon F Freedman; Mays El-Dairi; M Tariq Bhatti
Journal:  Open Neurol J       Date:  2011-01-26
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