OBJECTIVE: To assess growth patterns of 9-year-old children, some of whom had intrauterine growth restriction (IUGR). METHOD: 75 9-year-old children (41 were IUGR infants) were weighed and measured at birth, at 1 year, at 2 years and at 9 years of age. Using general linear models for continuous data, changes in weight z scores were used to quantify growth rate between birth and 9 years of age. RESULTS: IUGR children were smaller at birth (weight z score -2.1 v 0.2 in normal children; p<0.001) but showed a greater increase in their weight between birth and 9 years (change of weight z score 1.5 v 0.4 in normal children; p = 0.001). At the age of 9 years the weight, height and body mass index (BMI) z scores were lower in IUGR children than the control children (weight z score -0.4 v 0.6, respectively; p<0.001, height z score -0.5 v 0, respectively; p = 0.002, BMI z score -0.2 v 0.7, respectively; p = 0.002). The predictors of these differences were IUGR, birth weight and maternal and paternal heights. CONCLUSION: IUGR infants grow faster but remain shorter and lighter than their normal counterparts-that is, they fail to fully catch up by 9 years of age.
OBJECTIVE: To assess growth patterns of 9-year-old children, some of whom had intrauterine growth restriction (IUGR). METHOD: 75 9-year-old children (41 were IUGR infants) were weighed and measured at birth, at 1 year, at 2 years and at 9 years of age. Using general linear models for continuous data, changes in weight z scores were used to quantify growth rate between birth and 9 years of age. RESULTS: IUGR children were smaller at birth (weight z score -2.1 v 0.2 in normal children; p<0.001) but showed a greater increase in their weight between birth and 9 years (change of weight z score 1.5 v 0.4 in normal children; p = 0.001). At the age of 9 years the weight, height and body mass index (BMI) z scores were lower in IUGR children than the control children (weight z score -0.4 v 0.6, respectively; p<0.001, height z score -0.5 v 0, respectively; p = 0.002, BMI z score -0.2 v 0.7, respectively; p = 0.002). The predictors of these differences were IUGR, birth weight and maternal and paternal heights. CONCLUSION: IUGR infants grow faster but remain shorter and lighter than their normal counterparts-that is, they fail to fully catch up by 9 years of age.
Authors: Lisa A Joss-Moore; Yan Wang; Michael S Campbell; Barry Moore; Xing Yu; Christopher W Callaway; Robert A McKnight; Mina Desai; Laurie J Moyer-Mileur; Robert H Lane Journal: Early Hum Dev Date: 2010-03-12 Impact factor: 2.079
Authors: Linda L LaGasse; Ronnesia B Gaskins; Henrietta S Bada; Seetha Shankaran; Jing Liu; Barry M Lester; Charles R Bauer; Rosemary D Higgins; Abhik Das; Mary Roberts Journal: Neurotoxicol Teratol Date: 2010-11-23 Impact factor: 3.763