Literature DB >> 17299646

A convenient new procedure for converting primary amides into nitriles.

Chun-Wei Kuo1, Jia-Liang Zhu, Jen-Dar Wu, Cheng-Ming Chu, Ching-Fa Yao, Kak-Shan Shia.   

Abstract

An operationally simple and high-yielding procedure has been developed for the conversion of primary amides to the corresponding nitriles, using ethyl dichlorophosphate/DBU as the mild dehydrating agent.

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Year:  2006        PMID: 17299646     DOI: 10.1039/b614061k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  5 in total

1.  Asymmetric catalytic N-phosphonyl imine chemistry: the use of primary free amino acids and Et2AlCN for asymmetric catalytic Strecker reaction.

Authors:  Parminder Kaur; Suresh Pindi; Walter Wever; Trideep Rajale; Guigen Li
Journal:  J Org Chem       Date:  2010-08-06       Impact factor: 4.354

2.  Crystal structures of the carbamoylated and cyanated forms of HypE for [NiFe] hydrogenase maturation.

Authors:  Taiga Tominaga; Satoshi Watanabe; Rie Matsumi; Haruyuki Atomi; Tadayuki Imanaka; Kunio Miki
Journal:  Proc Natl Acad Sci U S A       Date:  2013-12-02       Impact factor: 11.205

3.  Improved Schmidt Conversion of Aldehydes to Nitriles Using Azidotrimethylsilane in 1,1,1,3,3,3-Hexafluoro-2-propanol.

Authors:  Hashim F Motiwala; Qin Yin; Jeffrey Aubé
Journal:  Molecules       Date:  2015-12-29       Impact factor: 4.411

4.  Beckmann rearrangement of ketoximes induced by phenyl dichlorophosphate at ambient temperature.

Authors:  Chun-Wei Kuo; Min-Tsang Hsieh; Shijay Gao; Yi-Ming Shao; Ching-Fa Yao; Kak-Shan Shia
Journal:  Molecules       Date:  2012-11-20       Impact factor: 4.411

5.  Facile Conversion of Aryl Amines Having No α-Methylene to Aryl Nitriles.

Authors:  Shyamkanhai S Moirangthem; Dini Ahanthem; Sanatombi D Khongbantabam; Warjeet S Laitonjam
Journal:  ACS Omega       Date:  2022-08-22
  5 in total

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