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Literature DB >> 17297970

"Click" modification of silica surfaces and glass microfluidic channels.

Shaurya Prakash¹, Timothy M Long, John C Selby, Jeffrey S Moore, Mark A Shannon.

Abstract

This paper demonstrates a chemical surface modification method for covalent attachment of various polymers by using silane-based "click" chemistry on silica surfaces and within glass microchannels suitable for CE systems. Modified surfaces are characterized by contact angle measurements, X-ray photoelectron spectroscopy, and Fourier transform infrared-attenuated total reflection spectroscopy. Electroosmotic flow (EOF) measurements in modified and unmodified channels are provided. Spectroscopic and transport data show that various polymers can be covalently attached to glass surfaces with a measurable change in EOF.

Entities: Chemical

Mesh：

Substances：
Polymers
Silicon Dioxide

Year: 2007 PMID： 17297970 DOI： 10.1021/ac061824n

Source DB: PubMed Journal: Anal Chem ISSN： 0003-2700 Impact factor: 6.986

Keyword Cloud
Cited

7 in total

1. Biofunctionalization on alkylated silicon substrate surfaces via "click" chemistry.

Authors: Guoting Qin; Catherine Santos; Wen Zhang; Yan Li; Amit Kumar; Uriel J Erasquin; Kai Liu; Pavel Muradov; Barbara Wells Trautner; Chengzhi Cai
Journal: J Am Chem Soc Date: 2010-10-29 Impact factor: 15.419

2. Multi-Layer Micro-Nanofluidic Device for Isolation and Capture of Extracellular Vesicles Derived from Liposarcoma Cell Conditioned Media.

Authors: Prashanth Mohana Sundaram; Lucia Casadei; Gonzalo Lopez; Danielle Braggio; Gita Balakirsky; Raphael Pollock; Shaurya Prakash
Journal: J Microelectromech Syst Date: 2020-07-14 Impact factor: 2.417

"Click" modification of silica surfaces and glass microfluidic channels.

1. Biofunctionalization on alkylated silicon substrate surfaces via "click" chemistry.

2. Multi-Layer Micro-Nanofluidic Device for Isolation and Capture of Extracellular Vesicles Derived from Liposarcoma Cell Conditioned Media.

3. Surface molecular property modifications for poly(dimethylsiloxane) (PDMS) based microfluidic devices.

4. Electrochemically protected copper(I)-catalyzed azide-alkyne cycloaddition.

5. Silica nanoparticles functionalized via click chemistry and ATRP for enrichment of Pb(II) ion.

6. Cross-flow microfiltration for isolation, selective capture and release of liposarcoma extracellular vesicles.

7. Fabrication of device with poly(N-isopropylacrylamide)-b-ssDNA copolymer brush for resistivity study.